Original Publication Date: 1 June, 2018
Publication / Source: Bioanalysis 10(12)
Authors: Shi Y, Gao Y, Parys MV, Miller D, Milanowski D, Dean B and Liang X
Aim: Investigation of bile acids (BAs) as biomarkers for liver and kidney diseases has gained momentum recently to fulfill the needs in drug development and clinical practice, but a thorough and rapid profiling of BAs in human plasma has been hindered by the large interindividual variability and lack of selective methods.
Results: A selective and efficient UPLC-high resolution mass spectrometry method was developed and