Could new software make it possible to accurately measure highly concentrated samples without dilution?

Written by Alex Hyde, Future Science Group

“With the ability to quickly verify the quality of their samples, spectroscopists may spend less time on data analysis and more time on method development.” – Karnel Walker, Global Business Director of UV-vis spectroscopy (Thermo Fisher Scientific)

American biotechnology product development company, Thermo Fisher Scientific (MA, USA) have announced the release of the Thermo Scientific NanoDrop QC software. The new software, designed for use with the Thermo Scientific NanoDrop OneC spectrophotometer, could help scientists to quickly and accurately measure the concentration of different components in liquid samples. Additional features could enable scientists to measure highly concentrated samples without dilution.

The UV-vis microvolume NanoDrop OneC spectrophotometer shortens pedestal lengths based on sample absorbance. This feature is designed to allow users to measure highly concentrated samples without dilution. Such measurements could save time during sample preparation and reduce the cost and chemical waste associated with using large quantities of solvents for sample dilution.

In tandem with the NanoDrop OneC spectrophotometer, the new software could streamline workflows by eliminating time consuming steps. By negating the need for serial dilutions and the use of quartz cuvettes in favor of pipetting highly concentrated samples directly onto the pedestal, workflow efficiency could be increased.

The NanoDrop OneC spectrophotometer natively uses chemometric methods and is reportedly able to provide the results of a chemometric analysis in approximately 10 seconds.

Chemometrics is the chemical discipline that uses mathematical and statistical methods to design or select optimal procedures and experiments and to provide maximum chemical information by analysing chemical data.” – The Journal of Chemometrics and Intelligent laboratory systems.

Karnel Walker, Global Business Director of UV-vis spectroscopy (Thermo Fisher Scientific) explained: “The NanoDrop OneC is poised to save industrial customers an enormous amount of time. With the ability to quickly verify the quality of their samples, spectroscopists may spend less time on data analysis and more time on method development.”


Sources: http://thermofisher.mediaroom.com/2020-01-21-New-Thermo-Scientific-NanoDrop-QC-Software-Simplifies-Sample-Quality-Control-for-Industrial-Users; https://www.journals.elsevier.com/chemometrics-and-intelligent-laboratory-systems