Bioanalysis Zone

Patient Centricity and the Evolving Role of Microsampling



Far more patient-centric than venipuncture, Volumetric Absorptive Microsampling (VAMS™) using the Mitra® device from Neoteryx (Coventry, UK) allows patients to self-collect accurate and precise µL volumes of blood using a minimally invasive finger stick. More recently, advancements in integrated device technology by Tasso Inc. (WA, USA) support the pain-free collection of replicate microsamples from the upper arm, simplified by push-button activation. With the Mitra® and Tasso devices representing the majority of microsampling approaches supported by Altasciences (QC, Canada), this webinar examines both the bioanalytical workflows and clinical correlations required to successfully implement these techniques into a drug development program, with case studies highlighting the value of self-sampling.

What will you learn?

  • Key advantages of Mitra® VAMS™ and Tasso Inc. technology for blood microsampling
  • Bioanalytical workflows and assessments necessary to successfully validate methodology supporting the analysis of Mitra® microsamples
  • Critical correlations required in a clinical validation to demonstrate suitability of microsampling for exposure measurements

Who may this interest?

  • New and current practitioners of microsampling (clinicians, scientists, medical doctors)
  • Bioanalytical laboratories supporting the analysis of Mitra® microsamples
  • Key decision makers outsourcing preclinical/clinical programs incorporating microsampling


Jeff P circle headshotJeff Plomley, MSc
Scientific Director, Method Development

Jeff Plomley began his research career in the Gas Phase Ion Chemistry Laboratory of Prof. Raymond E. March as a Research Scientist designing novel ion trap scan functions to support applications development (ON, Canada). He then joined Thermo Instruments Canada as an Applications Marketing Chemist, then SCIEX (MA, USA) as a Senior Scientist in Product Definition and Core Research. Jeff has worked in both the preclinical and clinical CRO environment since 2001, developing over 250 de novo LC–MS/MS assays. He has contributed to the publication of over 25 peer-reviewed papers, 70 scientific posters and tech pubs, holds patents on MS instrumentation and frequently blogs and presents on microsampling workflows and advanced MS techniques. Jeff’s current research interests include applications development involving ion-mobility spectrometry and the implementation of microsampling technology into patient-centric medical devices. Jeff holds a master’s degree in Chemistry from Queens University in Kingston, Ontario, Canada.

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