View time: 2:29 mins
In this interview, Anne Kleinnijenhuis (Triskelion; Zeist, The Netherlands) describes his current research focus, key challenges he faces when utilizing LC–MS and what he believes the future is for the technology.
We talk to Germán Augusto Gómez-Ríos about shifting the paradigm of direct sample introduction to MS.
View time: 5 mins
In this first part of our first ‘In the lab’ series Scott Summerfield, Worldwide Head of Bioanalysis at GlaxoSmithKline (Ware, UK), talks through the basics of mass spectrometry.
Read time: 3:30 mins
The value of lipid biomarkers for precision medicine is growing in recognition, resulting in an increased research focus on translational lipidomic workflows. Underpinning advances in this field are developments in mass spectrometry (MS) and liquid chromatography (LC). In this editorial, David Peake (Thermo Fisher Scientific) considers the analytical challenges associated with translational lipid biomarker development, and how the latest LC–MS technologies and lipidomics workflows are overcoming them.
Watch time: 6:47 mins
Rainer Bischoff (University of Groningen; Groningen, The Netherlands) explains his current research focus with an emphasis on developing novel methods for protein, peptide and metabolite analysis in this video interview.
Read time: 3:15 mins
We talk to Panagiotis Vorkas about expanding lipidome coverage using MS/MS-aided untargeted data-independent RP-UPLC-TOF-MSE acquisition.
Read time: 4:30 mins
In this column, Afshin Safavi differentiates between ‘assay qualification’ and ‘assay validation’ explaining current industry guidance, the translation of this guidance into the exploratory biomarker world, and how Bioagilytix (NC, USA) approaches these challenges.
Read time: 4:45 mins
Eric Solon (Madrigal Pharmaceuticals; PA, USA) discusses whether or not IMS can replace QWBA as the technique of choice when examining the disposition of new drug and biotherapeutic entities.
Read time: 2:30 mins
We talk to Erin Baker about her article, Evaluating Lipid Mediator Structural Complexity Using Ion Mobility Spectrometry Combined with Mass Spectrometry, published in the Bioanalysis Special Focus Issue on lipidomics.