We talk to Amanda King-Ahmad about her work on the peptide-based glucagon-like peptide-1 receptor agonist liraglutide in this interview as part of our author’s perspective series.
In this interview, Stephane Moreau (Shimadzu Europa) introduces the new Q-TOF LCMS-9030 instrument among other technologies available for automation and microsamping.
In this Bioanalysis Zone interview, Shane Needham (Alturas Analytics; ID, USA) discusses the advantages and disadvantages of the technologies employed by Alturas Analytics, including microflow LC–MS.
In this interview, Michael Schwenkert (Bio-Rad Laboratories) describes the challenges for development of CAR-T cell therapies that can be addressed using anti-idiotypic antibodies.
Find out more an electrochemiluminescent bridging immunogenicity assay used to measure anti-drug antibodies in human serum using an acid dissociation step in this poster from KCAS Bioanalytical & Biomarker Services (KS, USA).
All immunogenicity assessments present specific challenges. As a contract research organization (CRO), a major challenge we face is related to the lack of harmonization and standardization. Find out more in this editorial from a team at LGC (Cambridgeshire, UK).
In this methodology article from Bioanalysis, H Li et al. describe the use of the Mitra® microsampler for blood sampling, ELISA quantitation and PK analysis of two marketed therapeutic monoclonal antibodies administered to rats.
As part of our Spotlight on immunogenicity, we carried out a survey to gain an insight into the trends, challenges and developments associated with immunogenicity testing. We would like to thank everyone who was able to share their thoughts by taking part in the survey.