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Method establishment for discerned immunogenicity assessment of a recombinant glycoprotein containing nonhuman sialic acid Neu5Gc residues
This research article describes a validated electrochemiluminescent method for the detection of antidrug antibodies against both protein and Neu5Gc-containing glycan epitopes.
This festive season we have put together a ‘12 days of Christmas’ giveaway for you to explore and enjoy. As the year draws to a close you can catch up on the latest bioanalytical highlights as you unpack our 12 content pieces.
The fourth in our monthly column series highlighting the ‘hot topics’ throughout November.
For our Spotlight on emerging technologies, we spoke to Scott Summerfield (GSK) about some of the technologies emerging in the bioanalytical field, the advantages and challenges faced with these techniques, and the scope for these technologies to advance further.
In this conference report we discuss our highlights from the 10th Open Meeting of the European Bioanalytical Forum – a New Journey begins (Barcelona, Spain; 14–17 November).
Ion mobility spectrometry combined with high-resolution mass spectrometry: acquisition, analysis and application to drug metabolism studies
In discovery, the identification of the major routes of biotransformation allows medicinal chemists to design compounds with more desirable ADME properties. Dan and Jan discuss the use of ion mobility spectrometry combined with high-resolution mass spectrometry for these drug metabolism studies.
In this commentary, Melanie Anderson discusses the use of paper-based dried sampling technologies and how they can provide opportunities to collect biological samples in the dried state, which involves significantly smaller sample volumes than traditional sample collection approaches.
On Thursday 16th of November, at The Dome NH collection Hotel, Barcelona, Spain (previously Hesperia Tower), the Bioanalysis Zone team hosted an exclusive event to celebrate all things bioanalysis!