Researchers from King Saud University (Riyadh, Saudi Arabia) have developed a new ELISA technique, with increased sensitivity and selectivity, for the simple monitoring of bevacizumab levels in blood plasma.
In this month long feature, we bring you a collection of content focusing on the ‘hot topic’ of immuno-oncology.
Immunoprecipitation middle-up LC–MS for in vivo drug-to-antibody ratio determination for antibody–drug conjugates
In this article from Bioanalysis, the authors present a middle-up LC–MS approach for DAR analysis using prelabeled capture beads and in-house fabricated slit-plates.
Drug-target complex specific antibodies: In this interview we talk to Michael Schwenkert (Bio-Rad Laboratories) about the poster he presented at EBF 2017.
Method establishment for discerned immunogenicity assessment of a recombinant glycoprotein containing nonhuman sialic acid Neu5Gc residues
This research article describes a validated electrochemiluminescent method for the detection of antidrug antibodies against both protein and Neu5Gc-containing glycan epitopes.
MorphoSys (Munich, Germany) has announced that its licensee Janssen (Beerse, Belgium) has gained approval for Tremfya® in Europe. The monoclonal antibody is used for the treatment of plaque psoriasis.
Issue 20 of Bioanalysis volume 9 is now available, including an editorial surrounding the factors which may impact PK measurements of antibody therapeutics alongside the latest methodologies, research articles and discussions of current bioanalytical challenges. Find out more about the issue here, or on the Bioanalysis webpage.
Take a look inside Bio-Rad’s custom recombinant antibody facility. Learn from our antibody experts how…
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We want to assess and mitigate risk from pre-existing antibodies early within clinical development. Will pre-existing antibodies impact our clinical trial?
Interview with Michael Schwenkert (Bio-Rad Laboratories) on best practices for the characterization and quality control of anti-idiotypic antibodies for bioanalysis
We sat down with Michael Schwenkert, Technical Sales Manager for custom antibodies at Bio-Rad Laboratories,…