Webinar available to view on demand. This webinar will give an overview of immunogenicity assay development, explore the impact of anti-drug antibodies on bioanalysis and review relevant case studies discussing in-study cut-point and tolerance.
Webinar Q&A follow up – Development of neutralizing antibody assays to support clinical safety assessment: when is a cell-based assay required and what challenges can you expect?
Thank you everyone who attended our live webinar “Development of neutralizing antibody assays to support…
Development of neutralizing antibody assays to support clinical safety assessment: when is a cell-based assay required and what challenges can you expect?
Webinar available on demand. Join our webinar to learn about the critical parameters related to the development of cell-based assays, the expected challenges and how binding assays could potentially be an acceptable replacement.
Webinar available to view on demand. The application of differential mobility spectrometry to overcome selectivity and sensitivity challenges for both small and large molecule quantitation in bioanalysis.
Insulin assays have been used for decades, and although they were validated once upon a time, industry guidelines have since been updated, improved and changed. How do these old methods stand against modern needs and requirements?
BioAgilytix (NC, USA) have announced their partnership with Sword Bio (IL, USA), to expand their bioanalytical services to include Sword Bio’s detection platform for immunoassays.
Read time: 3 mins
In this installment, Robert discusses how to get to grips with metabolites; the ways in which metabolites may affect the performance and reliability of an assay, and what could be done to overcome them.
A sensitive method for the quantitation of the peptide-based glucagon-like peptide-1 receptor agonist liraglutide in plasma using microfluidics chromatography tandem MS
In this article, the authors discuss an LC–MS/MS assay for the quantitation of liraglutide, a peptide-based injectable glucagon-like peptide-1 receptor agonist, as a convenient alternative to the enzyme-linked immunosorbent assay.
Issue 23 of Bioanalysis volume 9 is now available, including an editorial discussing the matrix effects, a methodology on assay signaling and a White Paper on the rise of hybrid LBA/LCMS immunogenicity assays.