Researchers from the University of Birmingham (Birmingham, UK) and Newcastle University (Newcastle, UK) have investigated a key enzyme utilized by gut bacteria that could be developed as a biomarker for intestinal diseases.
Scientists have reported a blood biomarker test that could be used to identify individuals with multiple sclerosis whose condition is likely to deteriorate in the following year.
New study reports the discovery of urinary biomarkers with potential for rapid, non-invasive and cost-effective diagnosis of early-stage overactive bladder.
Researchers from the University of Pennsylvania School of Medicine (PA, USA) demonstrated in a multidisciplinary blinded study that a liquid biopsy was more accurate for detecting the early stages of pancreatic ductal adenocarcinoma other biomarkers alone.
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The use of atmospheric pressure ionization MS in biomarker detection is still in its infancy and extensive research and validation of methods would be required to ensure the development of robust, reproducible methods. In this editorial the use of API technology is discussed as it could truly revolutionize biomarker discovery and point-of-care measurements.
In this poster, the authors discuss the use of a Simoa Human IL-17A assay, which is a three-step digital immunoassay for the quantitation of total IL-17A in human serum.
Biomarkers are used to improve diagnosis and monitor a therapeutic response. During biomarker discovery ideal candidates are identified.
Proteomics-based tumor biomarker discovery has come a long way since the days of two-dimensional gels. A multi-biomarker panel could incorporate different classes of biomolecules so as to narrate the disease history in a holistic manner.