Browsing: biomarkers

spotlight Waters image for bz
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Bile acids are an important class of biological molecules that are generated in the liver and play a central role in various biological functions, including cholesterol homeostasis. Quantitative analysis for research of bile acids using LC-MS is complicated by the presence of many isomeric compounds.Historically, this has meant that throughput has been compromised in order to separate these isomeric compounds. Here we demonstrate how these compounds can be separated, without compromising throughput, using Waters® CORTECS UPLC Technology combined with negative mode electrospray ionization mass spectrometry. This application note is also part of a MetaboQuan-R method package.

Biomarkers Biomarkers Spotlight
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In this Spotlight, we will be revisiting some of the key issues raised in a previous Spotlight: Biomarkers (and biosensors), as well as investigating advancements in the field and the development of techniques. We will hear from experts in the field about the key challenges they face, how they overcome them and how their research is helping to advance the development of human healthcare.

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