In this Research Article, published by Bioanalysis, investigators from Case Western Reserve University (OH, USA) investigate whether different preanalytical blood processing techniques influence results of digital enzyme-linked immunosorbent assay (ELISA)-based assays for blood biomarkers.
Jisun HJ Lee and Jiangjiang Zhu discuss volatile organic compounds produced by the gut microbiome and their relationship with human health. They also examine volatilomics, a field of metabolomics dedicated to the detection and quantification of gut microbial volatile compounds to reveal their function in human health and metabolism.
A simple sweat collection and analysis device from Penn State University (PA, USA) and Xiangtan University (Xiangtan, China) could assist healthcare professionals with diagnosising and monitoring disease progression by measuring biomarkers, such as pH and glucose.
In a Bioanalysis perspective article, Rasa Santockyte (Bristol Myers Squibb, NJ, USA) explored the topic of critical reagents in LBAs and hybrid LC–MS assays. We caught up with Rasa to find out the latest in the field.
We carried out a survey to gain an insight into the trends, challenges and future outlook for biomarker discovery. We would like to thank everyone who took part in the survey – make sure you check out the results in our infographic.
John Smeraglia (UCB, Brussels, Belgium) explains how translational biomarkers fit into the bioanalytical landscape and how to select an appropriate analytical methodology when carrying out translational studies.
Researchers have identified a metabolic biomarker that could be used to track the progression of arrhythmogenic cardiomyopathy – a genetic heart muscle disease that can cause life-threatening ventricular arrhythmias.
In this interview Robert Nelson, Associate Director of Science and Innovation at Covance (Geneva, Switzerland) discusses the importance of biomarkers in drug development, describing key aspects in the current guidance and key considerations to make in the development and validation process.
Read the Bioanalysis Zone team’s top five take away messages from the 12th EBF Open Symposium, from automation to patient-centric sampling in this conference report.