In this commentary, Melanie Anderson discusses the use of paper-based dried sampling technologies and how they can provide opportunities to collect biological samples in the dried state, which involves significantly smaller sample volumes than traditional sample collection approaches.
For therapeutic drug development and monitoring, microsampling technology provides a breakthrough alternative
One useful way to think about volumetric absorptive microsampling (VAMS) technology is as the next generation of traditional dried blood spot (DBS) cards. It’s a simpler method that makes it easier to collect blood and prepare it for analysis. With minimal training, the microsampling process can be self-administered anywhere, through a procedure that is less difficult and generally less expensive than working with conventional venous blood. Other benefits include a more pleasant patient experience, which leads to greater adherence and compliance, and freer access to remote areas of the world.
Development and validation of an electrochemiluminescent ELISA for quantitation of oral insulin tregopil in diabetes mellitus serum
This methodology discusses how a sensitive ELISA method could be used to support accurate measurement of Tregopil insulin and its metabolites.
Boehringer Ingelheim has announced that the interchangeability study for their adalimumab biosimilar candidate has begun.
In this article Johannes Winkler discusses how the recent clinical successes prove that synthetic oligonucleotides are useful therapeutic agents and outlines some obstacles that need to be overcome for a more widespread and safe application.
In this interview we sat down with Neil Spooner of Spooner bioanalytical solutions and James Rudge, global microsampling specialist for Neoteryx, to discuss their experience in microsampling. They discussed important recent developments in the field and also shared their thoughts on what the future looked like for microsampling.
In this interview we caught up with Laura Mercolini from the University of Bologna (Italy) to discuss some of the novel and exciting applications of microsampling in sports drug testing.
Researchers from the University of Milan have demonstrated how a preclinical test may assist clinicians in diagnosing neurological disorders.
Advancing SRM-based proteomics for detection and quantitation of histone modifications in scarce clinical specimens
In this webinar, we will discuss ongoing technology improvements for targeted histone analysis in clinical samples.
In this special feature article from Monique Bodil van Neil, Elizabeth Groeber and Dawn Yates (all from Charles River), the authors trace the important involvement of bioanalysis in supporting pharmaceutical research from early discovery to clinical development.