We look at some of the highlights of our Twitter chat (#TalkProteomics), where we questioned panelists John Wilson, Ben Orsburn, Matthias Trost and Eduardo Chicano Gálvez about all things proteomics – from mass spectrometry to drug discovery.
Browsing: drug discovery
This editorial provides an insight into the development of proteomics as a tool for drug and biomarker discovery, pharmacodynamics and protein network elucidation; and where technology may be heading in the future.
Find out more about the latest news and developments in labs-on-chips in the investigation of gut inflammation and cellular responses in drug discovery in this round-up.
Find out more about the technologies involved in drug metabolism and what the future may hold for drug metabolism studies in drug discovery research in this ‘In the Zone’ feature.
As part of our focus, we present this podcast where we talk to Mark Savage who discusses how software tools can address certain challenges and bring forward compounds from discovery to development.
Quantitative whole body autoradiography (QWBA) and imaging mass spectrometry (IMS): can IMS replace QWBA to support regulated drug discovery and development
Read time: 4:45 mins
Eric Solon (Madrigal Pharmaceuticals; PA, USA) discusses whether or not IMS can replace QWBA as the technique of choice when examining the disposition of new drug and biotherapeutic entities.
A team from the University of Toronto (ON, Canada) has developed a method to produce geometric isoforms of drugs, potentially leading to improved efficiency.
The themed issue on ‘emerging technologies in mass spectrometry’ has now been published online! In this issue of Bioanalysis, authors share several emerging technologies in mass spectrometry that could, in the near future, provide dramatic changes to what is considered conventional bioanalysis.
Post-acquisition data mining techniques for LC–MS/MS-acquired data in drug metabolite identification
This review discusses the targeted and untargeted post-acquisition data mining techniques, which facilitate the drug metabolite identification. Learn more in this article from Bioanalysis.