In this feature, we peek behind the paper with Jing Yu and Amanda Hays (PRA Health Sciences, KS, USA) to gain insights into the key challenges of post sample collection whole blood stability. They explain the advantages of the lyse freeze method and how their approach, which has been demonstrated on Tregs, could be implemented in clinical trials that monitor other cellular markers.
Browsing: flow cytometry
In this presentation, Steve Kleiboeker (Viracor Eurofins; MO, USA) discusses CMV diagnostic testing; in particular the CMV T-cell immunity panel, which can help physicians predict which patients are at risk and be prepared to work with the patients pre-emptively before they develop the disease.
As part of our Spotlight on flow cytometry, we carried out a survey to gain an insight into the trends, challenges and developments associated with this technique – find out the results in this informative infographic.
Developed by over 40 international experts, this set of practical guidelines is useful to in vitro diagnostic (IVD) innovators, clinical laboratories, regulatory scientists, and laboratory inspectors.
In these three posters, Charles Rivers (MA, USA) discuss the challenges associated with flow cytometry validation, compare data generated against that by microscopy, and compile historical immunophenotyping data in preclinical species.
In this manuscript, the European Bioanalysis Forum presents additional practice guidance on the use of flow cytometry in the support of drug development programs and addresses areas that are not covered in the previous publications.
In this methodology video, Derek Davies (Francis Crick Institute; London, UK) and Rachael Walker (Babraham Institute; Cambridge, UK) give an overview of how flow cytometry works, why it is important and where the technique is heading in the future.
Discover more about how Charles River (MA, USA) employs flow cytometry to support mouse model development in this interview with Christoph Eberle and Stephen Festin.
Receptor occupancy measurement by flow cytometry is a rapid, quantifiable and an important addition to PK and PD data in the biopharmaceutical development process.
In this editorial, Reiner Schulte (Cambridge Institute for Medical Research, UK) discusses the market of flow cytometry analyzers and cell sorters, highlighting some interesting developments in the field of flow cytometry.