This article from Bioanalysis is focused on the challenges in the development of flow cytometry bioanalytical methods to quantitatively measure CAR-T cell levels in adoptive cell therapy.
Browsing: flow cytometry
2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 – LBA/cell-based assays: immunogenicity, biomarkers and PK assays)
This part of the 2018 White Paper published in Bioanalysis covers the recommendations for large molecule bioanalysis, biomarkers and immunogenicity using LBA and cell-based assays.
We talk to Vellalore Kakkanaiah about his work using flow cytometry in adoptive cell therapy in this interview as part of our author’s perspective series.
From the quantification and validation of biomarkers to the integration of novel technology in bioanalytical workflows, as the year comes to a close we’re looking back on the bioanalytical highlights from 2018.
In this feature, we will be investigating how flow cytometry works, key advances in technology over the years and how applications for flow cytometry detection and measurement are being developed.
Find out more about setting up and running any flow cytometry assay with this helpful infographic including the different platforms, instrumentation, data analysis software and example assay types.
We talk to Christoph Eberle, Principal Scientist at Charles River Laboratories (MA, USA). Christoph explains his fascination with flow cytometry, key advantages of the technique and where he hopes the field with be in 5–10 years’ time.
Best practices in performing flow cytometry in a regulated environment: feedback from experience within the European Bioanalysis Forum
In this manuscript, the European Bioanalysis Forum presents additional practice guidance on the use of flow cytometry in the support of drug development programs and addresses areas that are not covered in the previous publications.
We have developed a simple, cost-effective, and labor-efficient two-step protocol for preparing adherent cells for…
Flow cytometry is increasingly recognized as an invaluable technology in biomarker research. Owing to its multiparametric nature it can provide highly detailed information on any single cell in a heterogeneous population. Find out more in this review from Bioanalysis.