We talk to Laura Rowe about her work using UHPLC to analyse protein glycosylation in this interview as part of our author’s perspective series.
This review article from Bioanalysis> introduces the differences between UHPLC and HPLC, and reviews the use of UHPLC in the last 5 years when studying the glycosylation of proteins and glycoprofiling biopharmaceuticals.
Quantification of phenolic acid metabolites in humans by LC–MS: a structural and targeted metabolomics approach
In this research article from Bioanalysis, the authors quantified and identifed over 50 analytes from human biological matrices by HPLC, NMR and LC–MS to obtain structural information on phenolic acid metabolites.
Preclinical pharmacokinetics and biodistribution studies of asenapine maleate using novel and sensitive RP–HPLC method
This study investigates the pharmacokinetic and tissue distribution study of ASPM following oral administration in rats. Learn more in this study from Bioanalysis .
Researchers from the University of Colorado Anschutz Medical Campus (Aurora, Colorado, USA) have identified a biomarker in plasma that may serve as a predictor of epilepsy.
In this article, the authors discuss how some novel chromatographic approaches will be considered in terms of what they can offer the bioanalysts.
Comparison of selectivity and efficiency: two key factors in determining chromatographic resolution of components of a mixture
In this article Jim Taylor (Quotient Bioresearch) appraises selectivity and efficiency, two key factors critical in resolving components of a mixture, providing advice on how to tap into them effectively to help simplify and improve chromatographic separations.
This article features the presenters responses to unanswered audience questions posed during the live webinar ‘Webinar with the 2015 Young Investigator Award (YIA) winner’.
In this research article an isotope dilution HPLC/MS/MS method for the sensitive quantitation of nifurtimox down to 10.0 μg/l in plasma is described
In this research article a HPLC method for determination and enantiomeric resolution of dl-carnitine in human plasma is presented.