Available on demand. LC–MS based large molecule bioanalysis platform was developed, validated and applied for drug screening and preclinical pharmacokinetics.
This application note from Waters discusses a robust and reliable IA-LC-HRMS method for the qualitative analysis and quantification of ado-trastuzumab emtansine (T-DM1, Kadcyla™).
This poster from SCIEX (Warrington, UK) reports the use of an immunoaffinity high-resolution accurate mass assay as a complimentary analytical technique for signature peptide quantification.
Case Study: Cytokine Receptor α/β/γ Measured by Serial Immunoaffinity with Capture Microflow LC–MS/MS
Learn how using serial immunoaffinity (IA) enrichment and targeted MS offers the possibility to measure multiple protein targets with great sensitivity.
Improving selectivity and sensitivity of protein quantitation by LC–HR–MS/MS: determination of somatropin in rat plasma
Find out more this method to improve selectivity and sensitivity of protein quantitation by LC–HR–MS/MS in this free article from Bioanalysis.
Opportunities and challenges for hybrid immunoaffinity LC–MS approach for quantitative analysis of protein biomarkers
Learn more about opportunities and challenges for hybrid immunoaffinity LC–MS approach for quantitative analysis of protein biomarkers in this article from Future Science OA.