In this feature, we explore the key qualities to look for to ensure success when outsourcing immunogenicity assay development and testing. We also explore the methods for – and challenges involved with – T-cell immunity monitoring and assay development.
Browsing: in the zone
Assay development enables a drug or biochemical to be tested or measured. When analyzing a peptide of interest, it is important to choose and develop assays that are specific, sensitive and robust. There are many challenges when developing assays.
Bioanalysis is a critical part of the discovery and development of peptide therapeutics. In this In the Zone, we explore key bioanalytical challenges of peptide bioanalysis sample preparation.
In this feature, we will be investigating different alternative matrices that are available to the bioanalytical scientist and what questions need to be asked when deciding on the appropriate matrix to answer specific bioanalytical questions.
The future of alternative matrices in bioanalytical workflows: an interview with Amy Mize (KCAS Bioanalytical & Biomarker Services)
In this exclusive interview, Dr Amy Mize (KCAS Bioanalytical Services; KS, USA) describes how alternative matrices can be applied to bioanalytical studies and what challenges need to be addressed in order to introduce these matrices into bioanalytical workflows.
As part of our ‘In the Zone’ feature on drug metabolism, we present the top 6 tips for LC–MS for drug metabolism studies. Find out more about best practice tip and tricks for LC–MS in this helpful infographic from MilliporeSigma (MO, USA).
As part of our focus, we present this podcast where we talk to Mark Savage who discusses how software tools can address certain challenges and bring forward compounds from discovery to development.
In this feature, we present a collection of resources focusing on the ‘hot topic’ of biotransformation, including: an introduction to what it is, a podcast discussing the technologies used to characterize biotransformation and an infographic with our top 5 challenges for the biotransformation scientist and software solutions.