In this Bioanalysis Zone interview, Shane Needham (Alturas Analytics; ID, USA) discusses the advantages and disadvantages of the technologies employed by Alturas Analytics, including microflow LC–MS.
“There are, in essence, two schools of thought that I can perceive when discussions occur on the topic of appropriate purity of the laboratory water and various solvents, additives and reagents for any given stage of a quantitative bioanalytical procedure.” Find out more from Robert MacNeill (Envigo) in this editorial column.
As part of our ‘In the Zone’ feature on drug metabolism, we present the top 6 tips for LC–MS for drug metabolism studies. Find out more about best practice tip and tricks for LC–MS in this helpful infographic from MilliporeSigma (MO, USA).
Improving selectivity and sensitivity of protein quantitation by LC–HR–MS/MS: determination of somatropin in rat plasma
Find out more this method to improve selectivity and sensitivity of protein quantitation by LC–HR–MS/MS in this free article from Bioanalysis.
In this interview with Ragu Ramanathan (Pfizer; NY, USA), Ragu describes his current research focuses in measuring and quantitating drugs and metabolites in animal and human samples. Ragu discusses the key challenges associated with studying drug/drug interactions (DDI), the benefits of current technologies available for studying DDI and what to expect from the upcoming Special Focus Issue from Bioanalysis on ‘Novel LC–MS assays impacting CYP and transporter DDI evaluation’.
Opportunities and challenges for hybrid immunoaffinity LC–MS approach for quantitative analysis of protein biomarkers
Learn more about opportunities and challenges for hybrid immunoaffinity LC–MS approach for quantitative analysis of protein biomarkers in this article from Future Science OA.
In this interview, Nico and Chad (PRA Health Sciences; NC, USA) discuss the advantages, disadvantages and challenges they face with the technologies they utilize, before predicting what the future holds for the field.
Rob Wheller, Principal Scientist from LGC (Fordham, UK), discusses his current research focuses; the advantages, disadvantages and challenges of the technologies he utilizes; and advice he would give to young, early-career scientists.
Watch time: 2:44 mins
In November 2017 we interviewed Marco Michi, Scientific Officer – Technology Leader at Aptuit (Verona, Italy), about his research into LC–MS for ADA analysis.
View time: 8:50 mins
In this interview, Roland Staack and Gregor Jordan from Roche (Basel, Switzerland) talk about their recent publication, ‘Evaluation of the potential use of hybrid LC–MS/MS for active drug quantification applying the free analyte QC concept’.