Learn more about the positive impact of upfront systematic screening and characterization of conjugated critical reagent attributes on assay robustness in this methodology article in Bioanalysis.
Browsing: ligand-binding assay
As part of our Spotlight on LBA, we carried out a survey to gain an insight into the trends, challenges and developments associated with this technique. We would like to thank everyone who was able to share their thoughts by taking part in the survey – you can see the results below in our infographic.
Webinar available on demand. In this free panel discussion, our experts will provide insights into their own research using ligand binding assays including the challenges they have had to overcome, key trends they have seen and their future outlook on the development of this field.
In this interview, Jon Haulenbeek (Bristol-Myers Squibb; NJ, USA) discusses his role as a Group Leader running the Reagent Center of Excellence in the Translational Medicine Division.
Complete our short survey on ligand binding assays and be the first to receive our informative infographic collated from the survey results.
Scientists at Pfizer have reported a retrospective study of pharmacokinetics (PK) data that highlights the…
In this application note, Yun Alelyunas (Waters Corporation) describes an LC-HRMS method for high sensitivity bioanalysis of monoclonal antibodies by direct mass measurement at the intact level for whole molecule quantification. This emerging approach can serve as an alternative or complement to traditional methods such as ligand binding assay for protein quantification. Methodology and guidance for evaluating and optimizing data processing parameters are discussed in detail.
This article describes three case studies of a plug-and-play immuno polymerase chain reaction (iPCR) technique used to measure biomolecules. Learn more in this article from Bioanalysis.
Parallelism experiments to evaluate matrix effects, selectivity and sensitivity in ligand-binding assay method development: pros and cons
This review compares and discusses all available approaches that can be used to assess key assay parameters for pharmacokinetic and biomarker ligand-binding assays. Find out more in this article from Bioanalysis.