In this article from Bioanalysis, the authors give their perspectives and findings in exploring a hybrid LBA/LC–MS as an orthogonal bioanalytical tool for clinical immunogenicity assessments.
Browsing: mass spectrometry
In this interview, Ils Pijpers (Janssen R&D) discusses the challenges faced with sample preparation and method validation when using high-resolution mass spectrometry.
In this research article from Bioanalysis the authors discuss the quantitation of larger biotherapeutic proteins such as antibodies and antibody–drug conjugates compared with small molecules by LC–HRMS.
Development of two complementary LC–HRMS methods for analyzing sotatercept in dried blood spots for doping controls
In this research article from Bioanalysis the authors discuss the role of alternative matrices such as dried blood spots in sports drug testing, and the advantages these methods have over conventional matrices.
Hear more about the recent mass spectrometry product launches from SCIEX announced at ASMS 2019, including the new Acoustic Ejection Mass Spectrometry technology, in this interview with Neil Walsh (SCIEX; MA, USA).
An isobaric labeling technique has been developed to amplify signals for comprehensive quantitative phosphoproteomic characterization of small cells populations.
We talk to Vellalore Kakkanaiah about his work using flow cytometry in adoptive cell therapy in this interview as part of our author’s perspective series.
An author’s perspective: Zhengqi Ye on approaches to measure protein binding of enzymatically unstable compounds
We talk to Zhengqi Ye about the approaches she uses to measure protein binding of enzymatically unstable compounds in plasma in this interview as part of our author’s perspective series.
We talk to Laura Rowe about her work using UHPLC to analyse protein glycosylation in this interview as part of our author’s perspective series.