In this interview, Timothy Garrett (University of Florida, FL, USA) discusses the use of MS in his research, some of the key differences between imaging MS and LC–MS and gives some top tips for method development.
Browsing: mass spectrometry
Avacta (Cambridge, UK) has announced that the bead-assisted mass spectrometry test for COVID-19, currently in development with Adeptrix (MA, USA), has reached prototype stage.
High-resolution mass spectrometry has come a long way since its inception. As the field continues to evolve, take a look at the applications of HRMS. From exact mass to routine analyses, what’s next?
The use of atmospheric pressure ionization MS in biomarker detection is still in its infancy and extensive research and validation of methods would be required to ensure the development of robust, reproducible methods. In this editorial the use of API technology is discussed as it could truly revolutionize biomarker discovery and point-of-care measurements.
In this editorial Amandine Dispas (University of Liege, Belgium) discusses the versatility of SFC and the ongoing role of mass spectrometry in the latest chromatographic workflows. Does chromatography need mass spectrometry? Find out here.
In this editorial Isabelle Kohler (Vrije Univerisiteit Amsterdam, The Netherlands) explores the future of chromatography in bioanalysis. Is chromatography still a necessity in the face of developments in other analytical technologies?
Internal standards in regulated bioanalysis: putting in place a decision-making process during method development
In this perspective article from Bioanalysis the authors explore key considerations when selecting an IS and propose experiments to perform within the method development phase to demonstrate suitability of the IS within the assay prior to validation.
In this series of presentations, LGC (Cambridge, UK) explores whether high resolution mass spectrometry (HRMS) can challenge the ‘Gold Standard’ triple quadrupole mass spectrometer for quantitative bioanalysis within the CRO environment.
In this series of short, recorded presentations a team from Waters (MA, USA) discuss fundamental and practical details regarding large molecule quantification.
In this article from Bioanalysis, the authors give their perspectives and findings in exploring a hybrid LBA/LC–MS as an orthogonal bioanalytical tool for clinical immunogenicity assessments.