Learn more about a new robust method by which to measure sodium, potassium and creatine levels with clear improvements over some established methodology in this article from Bioanalysis.
A collection of helpful answers to the most frequently asked questions concerning the use of high-resolution mass spectrometry (HRMS) in drug metabolism and pharmacokinetics (DMPK).
On-line monitoring human breath acetone during exercise and diet by proton transfer reaction mass spectrometry
Learn about a method for determining breath acetone concentration using direct breath sampling and system-proton transfer reaction MS in this research article from Bioanalysis.
Discover more about a possible new avenue, free of ion-pairing, for general application in oligonucleotide quantitative LC–MS discovered by researchers in this methodology from Bioanalysis.
In this installment of Robert MacNeill’s (Covance) column, Robert discusses where to best place specific QC samples within a calibration range for a methodology, and the challenges associated with establishing suitable nominal levels for the internal standard concentration.
In this installment of Robert MacNeill’s (Envigo) column, Robert discusses methodologies for small lipids, and why these can be a particularly challenging area of biologics.
Find out more about some of the top stories this week in methodological improvements for the quantitative analysis of proteomes, and for the production of chiral molecules.
Read time: 00:30 mins
The US Food and Drug Administration (FDA) have announced a final guidance for industry, ’Bioanalytical Method Validation,’ is now available.
In this second part of our first ‘In the lab’ series, Scott Summerfield, Worldwide Head of Bioanalysis at GlaxoSmithKline (Ware, UK), talks through his five top tips and tricks for mass spectrometry.
View time: 5 mins
In this first part of our first ‘In the lab’ series Scott Summerfield, Worldwide Head of Bioanalysis at GlaxoSmithKline (Ware, UK), talks through the basics of mass spectrometry.