Boehringer Ingelheim has announced that the interchangeability study for their adalimumab biosimilar candidate has begun.
Current thinking on quantification of protein therapeutic pharmacokinetics and protein biomarkers in clinical studies
In this commentary, Kate Peng discusses the current thinking on quantification of protein therapeutic pharmacokinetics and protein biomarkers in clinical studies.
Interview with Michael Schwenkert (Bio-Rad Laboratories) on best practices for the characterization and quality control of anti-idiotypic antibodies for bioanalysis
We sat down with Michael Schwenkert, Technical Sales Manager for custom antibodies at Bio-Rad Laboratories,…
In this commentary, the author aims to provide some clarity on accuracy-related expectations for the regulated bioanalysis of ‘endogenous’ analytes.
In this publication Imperacer® case studies demonstrate the advantage of broad assay range combined with excellent sensitivity for several Biologics on their way from R&D to clinics.
In this application note, scientists outline best practices and recommendations for LBA reagents.
Bioanalysis and Bioanalysis Zone were proud to support the WRIB Poster Awards at the 10th WRIB – here we feature the three winning authors.
Skin sample preparation by collagenase digestion for diclofenac quantification using LC–MS/MS after topical application
In this research article, a new approach involving enzymatic treatment and mechanical homogenization techniques were evaluated for efficient sample preparation of skin samples.
Determination of ibuprofen enantiomers in human plasma by HPLC–MS/MS: validation and application in neonates
In this research articles the authors describe a reliable, precise and specific HPLC–MS/MS-based assay to quantify ibuprofen enantiomers in neonatal plasma samples.
In this research article various large molecules were analyzed using High-resolution and triple quadrupole mass spectrometers, the data generated resulted in identical PK parameters from an in-life sample set, giving confidence in either technique in support of biotherapeutic PK exposure studies.