In this interview, Anita Tailor (Merck) discusses biomarker validation and standardization before predicting what the future may hold for biomarker research.
In this Spotlight interview, Franklin Spriggs (KCAS; KS, USA) explains his interest in biomarkers and introduces the technologies and techniques utilized and offered by KCAS.
Find out more about the consequences of utilizing biomarker assays in drug development without being validated correctly, in this Perspective from Bioanalysis.
In this editorial, Robert MacNeill (Envigo) dicusses the case for the surrogate analyte approach for biomarker validation.
Find out more about ensuring the validity of biomarker measurements in this Editorial from Liam Heaney (University of Loughborough, UK).
Find out more about the validation of biomarkers in this interview with Hanna Ritzén, Managing Director Research and Development at Mercodia AB (Uppsala, Sweden).
To kick-start this special focus, we wanted to hear your thoughts on the topic – complete our short survey on the validation of biomarkers and be the first to receive our informative infographic collated from the survey results.
In this Spotlight, we will be revisiting some of the key issues raised in a previous Spotlight: Biomarkers (and biosensors), as well as investigating advancements in the field and the development of techniques. We will hear from experts in the field about the key challenges they face, how they overcome them and how their research is helping to advance the development of human healthcare.
Commercial assays for biomarker detection frequently utilize different reagents which each manufacturer considers proprietary. Subsequently, results may not match from vendor to vendor. Read how one group performed their own internal validation studies to address these concerns and effectively measure IL-6 and sIL-6R in patients following CAR T cell therapy.
Webinar available to view on demand. Single molecule counting (SMC™) technology enables precise measurement of molecules at levels previously undetectable, down to the femtogram/mL levels, allowing researchers to identify new biomarkers or assist in therapeutic development with an improved view of efficacy, safety and time course studies. Find out more in this video webinar from Millipore Sigma (MA, USA).