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Automation

Novel inertial microfluidic device could enhance sorting and purification of cells

Automation in Chinese bioanalytical CROs for sustained competitiveness and growth

Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices

Chromatography

A workflow for absolute quantitation of large therapeutic proteins in biological samples at intact level using LC-HRMS

Solid-phase extraction: a principal option for peptide bioanalytical sample preparation

Validation of a biotherapeutic immunoaffinity-LC–MS/MS assay in monkey serum: ‘plug-and-play’ across seven molecules

Clinical

Miniature biopsy-implantable biochemical sensor could assist clinicians against cancer

Novel biochip array may be used to detect Alzheimer’s risk

Analytical pitfalls and challenges in clinical metabolomics

Collaborations and Mergers

Mass Spectrometry vendors see potential growth opportunity in Africa

SCIEX and the University of Manchester partner to open £18m Stoller Biomarker Discovery Centre

Development of biopharmaceuticals to be advanced in university and industry partnership

Data Processing / Interpretation

Zoltan Takats talks about Perfecting your image – mass spectrometry

Interview with Roland Staack (Roche) on the nomenclature for large molecule assays recently developed at Roche

What will be the topic for our final Spotlight of 2016? You decide!

Drug Discovery and Development

Microneedle technology: the future of drug monitoring?

Antibody–drug conjugate bioanalysis using LB-LC–MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays

Characterization of matrix effects in developing rugged high-throughput LC–MS/MS methods for bioanalysis

Forensic

Disease pathogens rapidly detected by new test

Fingerprints: biological samples for identification of sex and, potentially, more

Method developed to uncover the age of a fingerprint

Imaging

Analyte identification strategies that complement imaging mass spectrometry

Imaging Mass Spectrometry at the 64th ASMS Conference for Mass Spectrometry and Allied Topics

Researchers develop a simple and economical micro-Raman system

Ligand-binding

Technical note (Bio-Rad): Characterization of critical reagents for ligand binding assays

Hybrid LBA/LC–MS technology increasingly gaining foothold in bioanalytical community

Antibody–drug conjugate bioanalysis using LB-LC–MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays

Mass Spectrometry

A workflow for absolute quantitation of large therapeutic proteins in biological samples at intact level using LC-HRMS

Researchers create MALDI-compatible protein chips by ambient ion landing

Validation of a biotherapeutic immunoaffinity-LC–MS/MS assay in monkey serum: ‘plug-and-play’ across seven molecules

Other

Miniature biopsy-implantable biochemical sensor could assist clinicians against cancer

Researchers discover novel prognostic biomarker for Mesothelioma

Ask the Experts on Microsampling ¦Stuart Kushon (Neoteryx)

Regulated Bioanalysis

Survey on Quantitative HRMS

Bioanalytical Specialty Section of Society of Quality Assurance Responds to your Questions

Electrically stimulated liquid-based extraction techniques in bioanalysis

Sample preparation, extraction & collection

Solid-phase extraction: a principal option for peptide bioanalytical sample preparation

Are diagnostics moving out of the microwell?

Paper chip could provide at-home malaria testing

Sports Drug Testing

Q&A With Monica Mazzarino & Franscisco Radler on key anti-doping issues

Special Feature on Anti-doping

Interview with Dr. Olivier Rabin (WADA): Challenges of Anti-doping analysis

Toxicology

Microneedle technology: the future of drug monitoring?

Nanotechnology used to improve biosensors for E. coli detection

Determination of free and conjugated forms of endocrine-disrupting chemicals in human biological fluids by GC−MS