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0Press Release: KCAS Bioanalytical and Biomarker Services Appoints Dr. Abu Siddiqui as Director, Large Molecule & Biomarker Bioanalysis
Kansas City, KS. – (May 2016) KCAS Bioanalytical and Biomarker Services, a leading bioanalytical and biomarker contract research organization (CRO) has welcomed Abu Siddiqui, Ph.D., as Director, Large Molecule & Biomarker Bioanalysis. Dr. Siddiqui has more than 15 years experiences designing, managing and executing biologics, vaccine and translational biomarker discovery studies for preclinical and clinical

Latest Features

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0Ask the Expert on Microsampling ¦Tim Sangster (Charles River)

In this ‘Ask the Expert’ feature we will be discussing recent developments in microsampling with some of the leading experts in the field.
In the instalment of Ask the Expert Tim Sangster, a bioanalytical chemist at Charles River shares with us his thoughts on the field.

Automation

Automation in Chinese bioanalytical CROs for sustained competitiveness and growth

Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices

Automation in Chinese bioanalytical CROs for sustained competitiveness and growth

Chromatography

Characterization of matrix effects in developing rugged high-throughput LC–MS/MS methods for bioanalysis

Conventional or hybrid? LC–MS assays at a crossroad

Hybridizing LBA with LC–MS/MS: the new norm for biologics quantification

Clinical

Novel neutrophil chemotaxis test employs all-on-chip method

Biosensor detects molecules linked to Alzheimer’s and Parkinson’s

Silk matrix encapsulation technique may stabilize blood samples for longer periods

Collaborations and Mergers

Development of biopharmaceuticals to be advanced in university and industry partnership

Building partnerships with other CROs

Introducing our Quality Assurance feature in collaboration with the SQA BASS

Data Processing / Interpretation

Interview with Roland Staack (Roche) on the nomenclature for large molecule assays recently developed at Roche

What will be the topic for our final Spotlight of 2016? You decide!

Potential milestone reached in noninvasive detection of prostate cancer

Drug Discovery and Development

Characterization of matrix effects in developing rugged high-throughput LC–MS/MS methods for bioanalysis

Sensitive assays enable detection of serum IgG antibodies against Clostridium difficile toxin A and toxin B in healthy subjects and patients with Clostridium difficile infection

Interview with Roland Staack (Roche) on the nomenclature for large molecule assays recently developed at Roche

Forensic

Fingerprints: biological samples for identification of sex and, potentially, more

Method developed to uncover the age of a fingerprint

Technique may allow forensic scientists to distinguish between identical twins’ DNA

Imaging

Key considerations for clinical IMS instrumentation

New microfluidic devices engineered for longer shelf-life

2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3 – LBA, biomarkers and immunogenicity)

Ligand-binding

Conventional or hybrid? LC–MS assays at a crossroad

Biosensor detects molecules linked to Alzheimer’s and Parkinson’s

Convergence of LBA/LC–MS in bioanalysis of large molecules – Part 2

Mass Spectrometry

Membrane protein preparation strategies for IMS

Characterization of matrix effects in developing rugged high-throughput LC–MS/MS methods for bioanalysis

Conventional or hybrid? LC–MS assays at a crossroad

Other

Ask the Expert on Microsampling ¦Tim Sangster (Charles River)

Unique breath markers to be trailed that could potentially diagnose Malaria infection

Mass production of microvalves could see advancement of microfluidic devices

Regulated Bioanalysis

Bioanalytical Specialty Section of Society of Quality Assurance Responds to your Questions

Electrically stimulated liquid-based extraction techniques in bioanalysis

Considerations for evaluation of accuracy, parallelism and reagent lot-to-lot variability in single and multiplex biomarker ligand binding assays

Sample preparation, extraction & collection

Membrane protein preparation strategies for IMS

Novel neutrophil chemotaxis test employs all-on-chip method

Conventional or hybrid? LC–MS assays at a crossroad

Sports Drug Testing

Anti-doping device offers immediate results for drug testing

Analytical challenges and solutions in doping control: a perspective from the Swedish Doping Control Laboratory

Printing nanomaterials with plasma: the future of biological sensor manufacturing?

Toxicology

Multiple stage MS in analysis of plasma, serum, urine and in vitro samples relevant to clinical and forensic toxicology

Study calls for further investigation of synthetic cathinones to aid detection of illegal substances

Bioanalytical procedures and developments in the determination of alcohol biomarkers in biological specimens