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Automation

Novel inertial microfluidic device could enhance sorting and purification of cells

Automation in Chinese bioanalytical CROs for sustained competitiveness and growth

Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices

Chromatography

Advances in bioanalytical techniques to measure steroid hormones in serum

Special Focus Issue: Bioanalysis of Large Molecules by LC–MS

How analogous can solid-phase extraction and analytical liquid chromatography be?

Clinical

Nanotechnology used to improve biosensors for E. coli detection

Determination of free and conjugated forms of endocrine-disrupting chemicals in human biological fluids by GC−MS

Electronic nose in development for disease diagnoses

Collaborations and Mergers

Development of biopharmaceuticals to be advanced in university and industry partnership

Building partnerships with other CROs

Introducing our Quality Assurance feature in collaboration with the SQA BASS

Data Processing / Interpretation

Zoltan Takats talks about Perfecting your image – mass spectrometry

Interview with Roland Staack (Roche) on the nomenclature for large molecule assays recently developed at Roche

What will be the topic for our final Spotlight of 2016? You decide!

Drug Discovery and Development

Characterization of matrix effects in developing rugged high-throughput LC–MS/MS methods for bioanalysis

Sensitive assays enable detection of serum IgG antibodies against Clostridium difficile toxin A and toxin B in healthy subjects and patients with Clostridium difficile infection

Interview with Roland Staack (Roche) on the nomenclature for large molecule assays recently developed at Roche

Forensic

Fingerprints: biological samples for identification of sex and, potentially, more

Method developed to uncover the age of a fingerprint

Technique may allow forensic scientists to distinguish between identical twins’ DNA

Imaging

Zoltan Takats talks about Perfecting your image – mass spectrometry

Key considerations for clinical IMS instrumentation

New microfluidic devices engineered for longer shelf-life

Ligand-binding

Nanotechnology used to improve biosensors for E. coli detection

Conventional or hybrid? LC–MS assays at a crossroad

Biosensor detects molecules linked to Alzheimer’s and Parkinson’s

Mass Spectrometry

Advances in bioanalytical techniques to measure steroid hormones in serum

Could blood metabolic changes act as biomarkers for cancer treatment success?

Special Focus Issue: Bioanalysis of Large Molecules by LC–MS

Other

Poster presentations from the 10th Workshop on Recent Issues in Bioanalysis (WRIB)

Flow cytometric analysis of B, NK and T cell subpopulations in whole blood samples from non-human primate

Ask the Expert on Microsampling ¦Christopher James (AMGen, Inc.)

Regulated Bioanalysis

Bioanalytical Specialty Section of Society of Quality Assurance Responds to your Questions

Electrically stimulated liquid-based extraction techniques in bioanalysis

Considerations for evaluation of accuracy, parallelism and reagent lot-to-lot variability in single and multiplex biomarker ligand binding assays

Sample preparation, extraction & collection

Finding the needle in the haystack: A simple path to matrix removal and robust solid-phase extraction methods

Breath analysis tool to reduce antibiotic resistance

How analogous can solid-phase extraction and analytical liquid chromatography be?

Sports Drug Testing

Young scientists develop rapid meldonium testing prototype device

Flexible, wearable biosensor tracks chemical and electrophysiological signals simultaneously

IOC announces reanalysis of samples from the London 2012 Olympic Games

Toxicology

Nanotechnology used to improve biosensors for E. coli detection

Determination of free and conjugated forms of endocrine-disrupting chemicals in human biological fluids by GC−MS

Multiple stage MS in analysis of plasma, serum, urine and in vitro samples relevant to clinical and forensic toxicology