The Bioanalysis and Bioanalysis Zone teams are delighted to bring you the fourth edition of The Bioanalysis Glossary, which we hope continues to be regarded as an essential resource for everyone who works in bioanalysis or related fields. A total of 14 leading bioanalytical experts have been working closely with us to provide a comprehensive update, reflecting the constantly evolving and dynamic field of bioanalysis.

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What is Bioanalysis?

The quantitative or qualitative measurement of endogenous or exogenous analyte in biological matrices, including tissue, blood, serum, urine or other body fluids.

What is a Biomarker?

Protein or small molecule indicative of homeostasis or a disease state, the concentration of which can indicate disease progression or a response to a therapeutic intervention.

What is a Biosimilar?

Also known as ‘follow-on biologic’. Subsequent version of an innovator biologic product. Biosimilars are characterized as having the same amino acid sequence as the originator therapeutic and also nearly identical pharmacokinetics (PK) and biological activity.