LATEST WEBINARS
Live event: Tuesday 21 September 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
Altasciences’ experts share their most recent experience using Volumetric Absorptive Microsampling Mitra™ technology from product characterization to application development, highlighted with specific case studies.
Live event: Tuesday 26 September 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
In this presentation, the results of an exploration of HRMS for the quantitative determination of biopharmaceutical proteins and a comparison to nominal mass LC-MS/MS will be provided, including validation results and application to preclinical trials.
Live event: Thursday 7 September 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
Introduction of the Axolabs PNA-HPLC Assay for selective and sensitive bioanalysis of all kinds therapeutically relevant oligonucleotide entities up to 100nt in length.
Live event: Thursday 14 September 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
During this panel discussion, our experts will analyze key results from our survey on oligonucleotides, giving a comprehensive overview on the current applications and the future trends of oligonucleotide analysis.
Live event: Tuesday 22 August 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
All biological protein drugs are immunogenic, which may lead to severe clinical consequences. This makes knowledge of the scientific and regulatory aspects of immunogenicity a must for every drug manufacturer.
Bioanalysis Zone and the University of Wisconsin-Madison’s School of Pharmacy are delighted to present a collection of informative webinars on the latest hot topic areas for the bioanalytical community.
Available to view on demand: In this webinar Wayland Rushing outlines the common pitfalls that result in method transfer failures and how best to avoid them.
Available to view on demand: In this webinar, Adam Hill discusses the changes and challenges in early drug discovery, including new and more efficient discovery strategies.
Available to view on demand: In this webinar, Mattias Trost discusses High-throughput MALDI-TOF mass spectrometry for drug discovery in the ubiquitin system.
Available to view on demand: In this webinar Melanie Leveridge talks about the advancements in MALDI-TOF Mass Spectrometry towards Ultra High Throughput Screening.
Available to view on demand: In this webinar, Harley Wilcox outlines the eccentricity of method validation related to guidance and best practices, including a list of the most useful sources for validation reference.
Live event: Thursday 7 September 2017, 11:00 AM [CT]. In this webinar, Glenn Petrie discusses best practice in optimizing the Chemistry, Manufacturing and Control (CMC) process.
Latest News
Could two novel biomarkers change the standard in care and treatment of pancreatic ductal adenocarcinomas? Recent research suggests a change in preoperative prognoses and a step forward in personalized medicine.
Charles River Laboratories (MA, USA) have acquired Brains On-Line (CA,USA), a CRO specializing in therapeutics for the treatment of CNS diseases.
Novel technology, using single-color digital PCR, could enable the detection of cancerous DNA in circulating blood.
Latest Features
In this article the authors discuss GMP testing for oligonucleotide drug substance and drug product.
In this interview, Shalini Prasad from the University of Texas at Dallas (TX, USA), discusses her current research in the development of a multiplex diagnostic wearable.
In this interview, we talk to Omnia Ismaiel on her latest article, ‘Do we have mature LC–MS/MS methodology for therapeutic monoclonal antibody bioanalysis?’.
Automation
Novel inertial microfluidic device could enhance sorting and purification of cells
Automation in Chinese bioanalytical CROs for sustained competitiveness and growth
Chromatography
Researchers identify candidate biomarkers for onset of osteoporosis
Could metabolomic profiling lead to earlier diagnosis of H1N1 influenza pneumonia?
Clinical
Boehringer Ingelheim’s adalimumab biosimilar candidate enters interchangeability study with HUMIRA®
Could a blood test detect the risk of cardiovascular disease in asymptomatic patients with lupus?
Could eosinophils be biomarkers for chronic obstructive pulmonary disease?
Collaborations and Mergers
Brains On-Line acquired by Charles River Laboratories
LGC obtain LINK technology to enhance oligonucleotide capabilities
Data Processing / Interpretation
Immunosensor developed for biotin detection
Drug Discovery and Development
Recent aspects and challenges in the assessment of immunogenicity
BIOCAD’s rituximab biosimilar receives recommendation for approval in India
‘Heart-on-a-chip’ engineered by Lawrence Livermore researchers
Forensic
Forensic scientists develop a new technique to distinguish the origins of bodily fluids
Disease pathogens rapidly detected by new test
Fingerprints: biological samples for identification of sex and, potentially, more
Imaging
Could chemiluminescence detect cancer?
Lung cancer recurrence detected earlier by circulating tumor cell test
Brain tumor progression and response to treatment tracked by new imaging biomarker
Ligand-binding
Mass Spectrometry
High-resolution mass spectrometry for the quantification of biopharmaceuticals
Insulin bioanalysis workflows simplified by new ready-to-use mass spectromic kit
Other
Poster presentations from the 11th Workshop on Recent Issues in Bioanalysis (WRIB)
BioPharmaSpec announce new in-house analytical services
TRUE-AHF is latest CRO-led international clinical trial reported to lack integrity
Regulated Bioanalysis
Study shows similarity in efficacy and safety between trastuzumab and its biosimilar candidate
FDA approval for first cancer treatment targeting solid tumors based on genetic characteristics
Pfizer’s proposed biosimilar secures approval from FDA advisory committee
Sample preparation, extraction & collection
Sports Drug Testing
Microsampling in sports drug testing – an interview with Laura Mercolini (University of Bologna)
Q&A With Monica Mazzarino & Franscisco Radler on key anti-doping issues
Toxicology
Bioanalysis and toxicology challenges with ADC: how are they different and new?