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Automation

Novel inertial microfluidic device could enhance sorting and purification of cells

Automation in Chinese bioanalytical CROs for sustained competitiveness and growth

Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices

Chromatography

Researchers identify candidate biomarkers for onset of osteoporosis

Could metabolomic profiling lead to earlier diagnosis of H1N1 influenza pneumonia?

The specifics of control matrices: How far to go?

Clinical

Novel breath test to predict kidney failure

Could glaucoma damage be predicted?

Could a blood test predict the outcome of prostate cancer treatment?

Collaborations and Mergers

Patheon to be bought by Thermo Fisher

Mass Spectrometry vendors see potential growth opportunity in Africa

SCIEX and the University of Manchester partner to open £18m Stoller Biomarker Discovery Centre

Data Processing / Interpretation

Could a blood test detect infant abusive head traumas?

Ask the Experts - Metabolomics

Capillary electrophoresis mass spectrometry as a tool for untargeted metabolomics

Drug Discovery and Development

‘Heart-on-a-chip’ engineered by Lawrence Livermore researchers

Could a blood test predict the outcome of prostate cancer treatment?

Plasma protein binding monitoring of therapeutic drugs in patients using single set of hollow fiber centrifugal ultrafiltration

Forensic

Forensic scientists develop a new technique to distinguish the origins of bodily fluids

Disease pathogens rapidly detected by new test

Fingerprints: biological samples for identification of sex and, potentially, more

Imaging

Could chemiluminescence detect cancer?

Lung cancer recurrence detected earlier by circulating tumor cell test

Brain tumor progression and response to treatment tracked by new imaging biomarker

Ligand-binding

3-(4-Hydroxyphenyl)propionic acid: the forgotten detection substrate for ligand-binding assay-based bioanalysis

Validation of a ligand-binding assay for active protein drug quantification following the ‘free analyte QC concept’

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 – small molecules, peptides and small molecule biomarkers by LCMS)

Mass Spectrometry

Researchers identify candidate biomarkers for onset of osteoporosis

Could metabolomic profiling lead to earlier diagnosis of H1N1 influenza pneumonia?

Quantification of proteins in complex biological samples by LC-MS/MS

Other

BioPharmaSpec announce new in-house analytical services

TRUE-AHF is latest CRO-led international clinical trial reported to lack integrity

MilliporeSigma announces launch of new protein detecting platform

Regulated Bioanalysis

Researchers urge FDA to update drug approval standards for Alzheimer’s drugs

From patient to tube: the importance of physiologically relevant quantitative bioanalytical assays

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 – small molecules, peptides and small molecule biomarkers by LCMS)

Sample preparation, extraction & collection

Could a blood test accurately predict Autism?

The specifics of control matrices: How far to go?

Ask the Experts - Metabolomics

Sports Drug Testing

Microsampling in sports drug testing – an interview with Laura Mercolini (University of Bologna)

Q&A With Monica Mazzarino & Franscisco Radler on key anti-doping issues

Special Feature on Anti-doping

Toxicology

Bioanalysis and toxicology challenges with ADC: how are they different and new?

Determination of propranolol and carvedilol in urine samples using a magnetic polyamide composite and LC–MS/MS

Microneedle technology: the future of drug monitoring?