LATEST WEBINARS
Webinar live date: Thursday 5 September 2019 07:00 [PDT] 10:00 [EDT] 15:00 [BST]. This webinar will discuss considerations for biomarker assay design and technology selection, including singleplex and multiplex ligand binding and immunometric assays, as well as optimization of pre-analytical factors and core assay performance expectations.
Webinar live date: 10 September 2019 07:00 [PDT] 10:00 [EDT] 15:00 [BST]. Join us for a discussion on proactive, effective and efficient bioanalytical project management.
Webinar available to view on demand. Learn about the most advanced methods for quantitating and characterizing therapeutic oligonucleotides.
Webinar available to view on demand. Register for our exclusive panel discussion focusing on the new ICH M10 guideline on bioanalytical method validation.
Webinar available to view on demand. Join us for a discussion on how bioanalytical data is used in early-phase clinical trials to advance drug development.
Webinar available to view on demand. Learn how using serial immunoaffinity (IA) enrichment and targeted MS offers the possibility to measure multiple protein targets with great sensitivity from a single sample.
Panel discussion available to view on demand. In this free panel discussion, our experts will provide insights into their own research using flow cytometry including the challenges they have had to overcome, key trends they have seen and their future outlook on the development of this field.
Webinar available to view on demand. Register for our exclusive Coffee Chat focusing on patient-centric sampling. This informal discussion centers on this new type of workflow that benefits the patient, enabling the collection of previously difficult data.
Available to view on demand. Receptor occupancy measurement by flow cytometry is a rapid, quantifiable and an important addition to PK and PD data in the biopharmaceutical development process.
Webinar available to view on demand. Quantitative, sensitive and specific bioanalytical methods for the investigation of therapeutic oligonucleotides in biological matrices
Latest News
Wearable skin sensors developed by researchers at the University of California (Berkeley, USA) could be able to provide real-time updates on dehydration and fatigue by providing measurements of electrolytes and metabolites in perspiration as well as record perspiration rates.
A new proteomics technique, termed ubiquitin clipping, has been developed to further understanding of changes that control protein function and their role in healthy and disease states.
Researchers develop a new simplified mass spectrometric technique using a continuous laser and graphene, thus shortening the preparation time before analysis.
Latest Features
In this interview, Ils Pijpers (Janssen R&D) discusses the challenges faced with sample preparation and method validation when using high-resolution mass spectrometry.
Antibody–drug conjugates (ADCs) combine the best of two modalities: toxic efficacy and antibody specificity. This infographic describes various mass spectrometry-based strategies Frontage have successfully applied in the bioanalysis of ADCs for clinical and preclinical studies.
In this interview, Jon Haulenbeek (Bristol-Myers Squibb; NJ, USA) discusses his role as a Group Leader running the Reagent Center of Excellence in the Translational Medicine Division.
Drug Discovery and Development
Drug detection in biological specimens: recent colorimetric methods
Signal amplification technology reveals previously undetectable proteins of disease
Bioanalytical laboratory considerations for immuno-oncology drug development
Ligand-binding
Perspectives on exploring hybrid LBA/LC–MS approach for clinical immunogenicity testing
Biotherapeutic characterization and quantification: an interview with Pegah Jalili
Mass Spectrometry
Perspectives on exploring hybrid LBA/LC–MS approach for clinical immunogenicity testing
LC–HRMS quantitation of intact antibody drug conjugate trastuzumab emtansine from rat plasma
A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers
Sample preparation, extraction & collection
Identifying critical quality attributes using Agilent AdvanceBio Columns