LATEST WEBINARS
Live event: Thursday 19 October 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
We want to assess and mitigate risk from pre-existing antibodies early within clinical development. Will pre-existing antibodies impact our clinical trial?
Live event: Thursday 12 October 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
Gain first-hand experience from a CRO on their transition from small molecule bioanalysis to biologics.
Available to view on demand: In this webinar, Glenn Petrie discusses best practice in optimizing the Chemistry, Manufacturing and Control (CMC) process.
Live event: Tuesday 3 October 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
This webinar will explore this continuum of fit-for-purpose validation, from the validation of early exploratory biomarker analysis, to the amalgamation of FDA GLP and CLIA GLP biomarker validation guidelines in the bioanalytical lab.
Available to view on demand: In this webinar, Kenneth Brouwer outlines the initiating events and the hepatocyte’s response in the regulation of bile acids.
In this webinar Kyunghee Yang and Kenneth Brouwer outline the species differences in the hepatobiliary disposition and regulation of bile acids.
Live event: Thursday, Oct 5, 2017 5:00 PM – 6:00 [BST].
In this webinar, James Schmidt discusses stereo-selectivity in drug metabolism.
Live event: Thursday 5 October 2017 at 08:00 [PDT] 11:00 [EDT] 16:00 [BST]
Experts in microsampling share their knowledge and experience of what is required to complete a successful implementation, with insights for anyone struggling with a new and disruptive technology.
Available on demand
Altasciences’ experts share their most recent experience using Volumetric Absorptive Microsampling Mitra™ technology from product characterization to application development, highlighted with specific case studies.
Live event: Tuesday 31 October 2017 at 07:00 [PDT] 10:00 [EDT] 14:00 [BST]
In this presentation, the results of an exploration of HRMS for the quantitative determination of biopharmaceutical proteins and a comparison to nominal mass LC-MS/MS will be provided, including validation results and application to preclinical trials.
Available to view on demand.
Introduction of the Axolabs PNA-HPLC Assay for selective and sensitive bioanalysis of all kinds therapeutically relevant oligonucleotide entities up to 100nt in length.
Available to view on demand
During this panel discussion, our experts will analyze key results from our survey on oligonucleotides, giving a comprehensive overview on the current applications and the future trends of oligonucleotide analysis.
Latest News
A recent metabolomics study has identified biomarkers from particular foods, which could help in establishing the connection between diet and Type 2 Diabetes, quantitatively.
Researchers have designed a camera capable of diagnostic optical spectroscopy, incorporated into the body of a smartphone.
Invicro, an imaging services company, announced the acquisition of Imanova, a UK-based imaging and translational research company.
Latest Features
In this review article the authors summarize the current development of functional oligonucleotides, called aptamers, focusing on the diagnostic and therapeutic applications.
Weiping Shao discusses biomarkers, immunogenicity and the work he contributes to at Regeneron Pharmaceuticals (NY,USA).
Bioanalysis Zone and Bioanalysis attended the 11th WRIB meeting in Los Angeles (CA, USA) and had the opportunity to host a panel discussion with experts from leading pharmaceutical companies and CROs to discuss several contemporary topics including: emerging technologies; recurring and talent development; and mergers and acquisitions.
Automation
Novel inertial microfluidic device could enhance sorting and purification of cells
Automation in Chinese bioanalytical CROs for sustained competitiveness and growth
Chromatography
Researchers identify candidate biomarkers for onset of osteoporosis
Could metabolomic profiling lead to earlier diagnosis of H1N1 influenza pneumonia?
Clinical
Point-of-care devices: the next frontier in personalized chemotherapy
Boehringer Ingelheim’s adalimumab biosimilar candidate enters interchangeability study with HUMIRA®
Could a blood test detect the risk of cardiovascular disease in asymptomatic patients with lupus?
Collaborations and Mergers
Brains On-Line acquired by Charles River Laboratories
LGC obtain LINK technology to enhance oligonucleotide capabilities
Data Processing / Interpretation
AYOXXA launches new beads-on-a-chip multiplex protein analysis system
Drug Discovery and Development
Recent aspects and challenges in the assessment of immunogenicity
BIOCAD’s rituximab biosimilar receives recommendation for approval in India
‘Heart-on-a-chip’ engineered by Lawrence Livermore researchers
Forensic
Forensic scientists develop a new technique to distinguish the origins of bodily fluids
Disease pathogens rapidly detected by new test
Fingerprints: biological samples for identification of sex and, potentially, more
Imaging
Could chemiluminescence detect cancer?
Lung cancer recurrence detected earlier by circulating tumor cell test
Brain tumor progression and response to treatment tracked by new imaging biomarker
Ligand-binding
Mass Spectrometry
High-resolution mass spectrometry for the quantification of biopharmaceuticals
Other
Poster presentations from the 11th Workshop on Recent Issues in Bioanalysis (WRIB)
BioPharmaSpec announce new in-house analytical services
TRUE-AHF is latest CRO-led international clinical trial reported to lack integrity
Regulated Bioanalysis
Study shows similarity in efficacy and safety between trastuzumab and its biosimilar candidate
FDA approval for first cancer treatment targeting solid tumors based on genetic characteristics
Pfizer’s proposed biosimilar secures approval from FDA advisory committee
Sample preparation, extraction & collection
Sports Drug Testing
Microsampling in sports drug testing – an interview with Laura Mercolini (University of Bologna)
Q&A With Monica Mazzarino & Franscisco Radler on key anti-doping issues
Toxicology
Bioanalysis and toxicology challenges with ADC: how are they different and new?