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Drug Discovery and Development

Development and validation of an ELISA to study panitumumab pharmacokinetics

Extended 3D and 4D cumulative plots for evaluation of unmatched incurred sample reanalysis

Combined mass spectrometry with robotic technologies technique could rapidly speed up drug discovery

Ligand-binding

3-(4-Hydroxyphenyl)propionic acid: the forgotten detection substrate for ligand-binding assay-based bioanalysis

Validation of a ligand-binding assay for active protein drug quantification following the ‘free analyte QC concept’

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 – small molecules, peptides and small molecule biomarkers by LCMS)

Mass Spectrometry

Targeting human urinary metabolome by LC–MS/MS: a review

Scientists in Russia develop a device for upgrading mass spectrometers and a novel biomarker is detected for the identification of the ‘window of opportunity’ for cancer chemotherapy timing

New service agreement between Owlstone Medical and AstraZeneca, Biosensis launch new BDNF/proBDNF biomarker kit and the 8th Conference on Current Trends in Mass Spectrometry and Chromatography is announced

Sample preparation, extraction & collection

Parallel Artificial Liquid Membrane Extraction of Psychoactive Analytes-a novel approach in therapeutic drug monitoring

An author's perspective: Astrid Gjelstad on Parallel Artificial Liquid Membrane Extraction (PALME)

Getting to grips with metabolites before the crunch of incurred samples