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Automation

Novel inertial microfluidic device could enhance sorting and purification of cells

Automation in Chinese bioanalytical CROs for sustained competitiveness and growth

Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices

Chromatography

The specifics of control matrices: How far to go?

Chromatography and Mass Spectrometry utilized to detect breast cancer earlier

LC–MS/MS strategies for therapeutic antibodies and investigation into the quantitative impact of antidrug-antibodies

Clinical

NGM Biopharmaceuticals announce product–NGM282–achieves primary endpoint in non-alcoholic steatohepatitis Phase II Trial

MCP-1 and cathepsin-D potential biomarkers for diabetic retinopathy

Could obstructive sleep apnea be diagnosed in children with Down syndrome utilizing biomarkers?

Collaborations and Mergers

Mass Spectrometry vendors see potential growth opportunity in Africa

SCIEX and the University of Manchester partner to open £18m Stoller Biomarker Discovery Centre

Development of biopharmaceuticals to be advanced in university and industry partnership

Data Processing / Interpretation

Could a blood test detect infant abusive head traumas?

Ask the Experts - Metabolomics

Capillary electrophoresis mass spectrometry as a tool for untargeted metabolomics

Drug Discovery and Development

NGM Biopharmaceuticals announce product–NGM282–achieves primary endpoint in non-alcoholic steatohepatitis Phase II Trial

New therapeutic target–HEG1–discovered for malignant mesothelioma

Travelling-wave ion mobility mass spectrometry exposes structure of gold fingers

Forensic

Forensic scientists develop a new technique to distinguish the origins of bodily fluids

Disease pathogens rapidly detected by new test

Fingerprints: biological samples for identification of sex and, potentially, more

Imaging

Lung cancer recurrence detected earlier by circulating tumor cell test

Brain tumor progression and response to treatment tracked by new imaging biomarker

Selected imaging publications from the National Research Resource for IMS

Ligand-binding

3-(4-Hydroxyphenyl)propionic acid: the forgotten detection substrate for ligand-binding assay-based bioanalysis

Validation of a ligand-binding assay for active protein drug quantification following the ‘free analyte QC concept’

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 – small molecules, peptides and small molecule biomarkers by LCMS)

Mass Spectrometry

Quantification of proteins in complex biological samples by LC-MS/MS

Forensic scientists develop a new technique to distinguish the origins of bodily fluids

Travelling-wave ion mobility mass spectrometry exposes structure of gold fingers

Other

MilliporeSigma announces launch of new protein detecting platform

Handheld chemical scanner proof-of-concept developed by researchers

Pharmaceutical Product Development (PPD) announces fifth renewal of contract with National Institutes of Health

Regulated Bioanalysis

From patient to tube: the importance of physiologically relevant quantitative bioanalytical assays

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 – small molecules, peptides and small molecule biomarkers by LCMS)

Accuracy: a potential quandary in regulated bioanalysis of ‘endogenous’ analytes

Sample preparation, extraction & collection

Could a blood test accurately predict Autism?

The specifics of control matrices: How far to go?

Ask the Experts - Metabolomics

Sports Drug Testing

Microsampling in sports drug testing – an interview with Laura Mercolini (University of Bologna)

Q&A With Monica Mazzarino & Franscisco Radler on key anti-doping issues

Special Feature on Anti-doping

Toxicology

Bioanalysis and toxicology challenges with ADC: how are they different and new?

Determination of propranolol and carvedilol in urine samples using a magnetic polyamide composite and LC–MS/MS

Microneedle technology: the future of drug monitoring?