Metabolomics is defined as the identification and quantification of metabolic products in a biological system. As part of this Spotlight, we explore the recent advances in target and untargeted metabolomics and review the use of metabolomics in drug development and precision medicine.
A biomarker is a protein or small molecule indicative of homeostasis or a disease state. As part of this Spotlight, we explore the different technologies used for biomarker discovery and what the future could hold.
In this Spotlight we will explore chromatographic separation technologies, the comparative advantages and disadvantages of different types and the history and developments with this powerful analytical technique.
In this Spotlight we will explore the advantages and challenges of HRMS, different software platforms and what the future could hold.
Welcome to this Bioanalysis Zone Spotlight, where we will explore the key developments of LBA, used for the quantification of large molecules.
In this Spotlight, we will explore recent developments in flow cytometry, advances in technology and the unique challenges that this type of analysis brings to the bioanalytical community.
In this mini-Spotlight we will be exploring the role of bioanalysis in cellular and gene therapies.
Welcome to this Bioanalysis Zone Spotlight, where we will explore the key developments and technologies in proteomics research.
In this Spotlight we will explore recent developments in immunogenicity, highlight key challenges when reviewing immunogenicity, and explore current regulations.
In this Spotlight, we will be revisiting some of the key issues raised in a previous Spotlight: Biomarkers (and biosensors), as well as investigating advancements in the field and the development of techniques. We will hear from experts in the field about the key challenges they face, how they overcome them and how their research is helping to advance the development of human healthcare.
In order to explore the most recent developments in large molecule quantification in regulated bioanalysis by LC–MS, this Spotlight will highlight the advances and challenges faced during method development, validation and samples analysis.
Welcome to this Bioanalysis Zone Spotlight, where we will explore the key developments and technologies in the ever-evolving field of small molecules.
In this Spotlight we will be exploring the recent developments and the unique challenges that oligonucleotides bring to the bioanalytical community.
Welcome to this Bioanalysis Zone Spotlight, where we will explore the bioanalysis of biopharmaceuticals and biomarkers.
In this Spotlight we explore the subject of outsourcing in the bioanalytical industry.
Welcome to the Bioanalysis Zone Spotlight on Quantitative HRMS! HRMS has been available for a long time; originally it was…
Welcome to the Bioanalysis Zone Spotlight on Hybrid LBA/LC-MS! LBA is historically the gold standard for biologics and is employed…
Welcome to the Bioanalysis Zone Spotlight on Large molecule analysis by LC-MS! In recent years there has been an increase…
Welcome to the Bioanalysis Zone Spotlight on Biomarkers (and biosensors)! A biomarker is “a characteristic that is objectively measured and…
Welcome to the Bioanalysis Zone Spotlight on antibody-drug conjugates (ADCs)! ADCs are dynamic, heterogeneous mixtures typically consisting of a cytotoxic…
Automation can increase throughput while maintaining quality; this increase in efficiency can lead to a reduction in the cost of…
Welcome to the Bioanalysis Zone Spotlight on Metabolomics! In recent years, metabolomics has become a ‘hot topic’ in bioanalysis; the…
Welcome to the Bioanalysis Zone Spotlight on Microsampling: the road ahead!
There has been continued interest in microsampling both in the literature and at scientific meetings in recent years, driven by factors including:
– Implications for 3Rs (replacement, reduction, refinement) in animal studies
– Maximizing information from animal pharmacology models in small animals
– Logistical benefits for clinical
Welcome to the Bioanalysis Zone Spotlight on ‘Hot topics in large molecule bioanalysis’! Hot on the heels of our hugely…
Welcome to the Bioanalysis Zone Spotlight on Overcoming Matrix Effects! Matrix effects are a major issue for the development and…
Dried blood spots (DBS) have been one of the hottest topics in bioanalysis in recent years. The potential benefits are…