Publication / Source: Bioanalysis 5(3)
Authors: Shi T, Qian WJ
“PRISM–SRM affords a unique protein quantification technology for biomarker verification and systems biologystudies where a large number of proteins need to be quantified from a set number of samples.”
In this postgenomic era there is a great demand in biomedical research for highly sensitive technologies that enable multiplexed detection and quantification of hundreds of low-abundance proteins and their modifications. For example, discovering effective biomarkers for improved prognosis/diagnosis of human diseases requires such technologies to rapidly verify and validate protein candidates.