Bioanalysis Zone

Astec CHIROBIOTIC chiral HPLC columns (Sigma-Aldrich)


Versatile chiral HPLC and LC-MS separations of polar, ionizable and neutral compounds

Astec CHIROBIOTICâ„¢ CSPs (chiral stationary phases) interact with polar, ionizable and neutral analytes via multiple molecular interactions. This versatility means that the same Astec CHIROBIOTIC column can be successfully used in a variety of mobile phases, a significant benefit over CSPs that operate only in a single mode, normal or reversed-phase, for example, and must be dedicated to those mobile phase systems. However, the most interesting feature of Astec CHIROBIOTIC CSPs is the presence of ionic interactions, which allows them to be used in polar ionic and reversed-phase modes for sensitive LC-MS operation.

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