Validation of methods for determining pediatric midazolam using wet whole blood and volumetric absorptive microsampling


In this methodology article from Bioanalysis, authors outline the validation of methods for determining pediatric midazolam using wet whole blood and volumetric absorptive microsampling. The authors successful method validation indicates the suitability of volumetric absorptive microsampling as a technique for pediatric clinical studies. Keywords: hematocrit, volumetric absorptive microsampling, method validation, microsampling, pharmacokinetics. For exclusive access to Bioanalysis journal articles, register to be a member of Bioanalysis Zone for free. Aim: The collection and quantitative analysis of dry blood using volumetric absorptive microsampling potentially offers significant advantages over conventional wet whole blood analysis. The manuscript published in Bioanalysis explores their use...

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