This research article describes a validated electrochemiluminescent method for the detection of antidrug antibodies against both protein and Neu5Gc-containing glycan epitopes.
In this article from Bioanalysis, the authors aim to demonstrate and evaluate the analytical performance of coupling the immediate drop on demand technology to a mass spectrometer via the recently introduced open port sampling interface and ESI.
This editorial discusses the use of mass spectrometry metabolomics as a diagnositic tool for detecting metabolic syndrome. Learn more in this article from Bioanalysis.
Issue 20 of Bioanalysis volume 9 is now available, including an editorial surrounding the factors which may impact PK measurements of antibody therapeutics alongside the latest methodologies, research articles and discussions of current bioanalytical challenges. Find out more about the issue here, or on the Bioanalysis webpage.
In this editorial, the author discusses how nanostructured materials can offer enhanced material properties and in particular hold great potential for fundamental advances in nanosensors.
This article describes three case studies of a plug-and-play immuno polymerase chain reaction (iPCR) technique used to measure biomolecules. Learn more in this article from Bioanalysis.
This article looks at a new electrochemiluminescence immunoassay developed to measure certolizumab pegol levels in human plasma. Learn more in this article from Bioanalysis.
This review discusses the targeted and untargeted post-acquisition data mining techniques, which facilitate the drug metabolite identification. Learn more in this article from Bioanalysis.
This review compares and discusses all available approaches that can be used to assess key assay parameters for pharmacokinetic and biomarker ligand-binding assays. Find out more in this article from Bioanalysis.
This study investigates the pharmacokinetic and tissue distribution study of ASPM following oral administration in rats. Learn more in this study from Bioanalysis .