This preliminary communication from Bioanalysis discusses the application of selected bile acids in plasma as endogenous probes for assessing drug–drug interactions involving hepatic drug transporters such as the organic anion-transporting polypeptides.
In this research article from Bioanalysis the authors discuss the role of alternative matrices such as dried blood spots in sports drug testing, and the advantages these methods have over conventional matrices.
In this White Paper from Bioanalysis the authors highlight the need the bioanalytical community has for commercial kits able to be used for regulated drug development.
In this report from Bioanalysis, the authors summaries key points discussed the Bioanalysis Zone panel discussion filmed during the 12th Workshop on Recent Issues in Bioanalysis which focused on the topic of new technology integration into bioanalytical workflows.
This commentary from Bioanalysis focuses on the status of drug detection with metal nanoparticles as ultrasmall labels in colorimetric-based methods.
In this methodology from Bioanalysis, the authors investigate the detection of Ki67 – a prognostic and/or predictive biomarker in patients with malignancies – in human blood using flow cytometry for single-cell multiparameter analysis.
This part of the 2018 White Paper published in Bioanalysis focuses on the recommendations for PK, PD and ADA assays by hybrid LBA/LCMS and regulatory agencies’ input.
This part of the 2018 White Paper published in Bioanalysis discusses the recommendations for LC–MS for small molecules, peptides, oligonucleotides and small molecule biomarkers.
This article from Bioanalysis is focused on the challenges in the development of flow cytometry bioanalytical methods to quantitatively measure CAR-T cell levels in adoptive cell therapy.