Take a look inside Bio-Rad’s custom recombinant antibody facility. Learn from our antibody experts how…
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We want to assess and mitigate risk from pre-existing antibodies early within clinical development. Will pre-existing antibodies impact our clinical trial?
Interview with Michael Schwenkert (Bio-Rad Laboratories) on best practices for the characterization and quality control of anti-idiotypic antibodies for bioanalysis
We sat down with Michael Schwenkert, Technical Sales Manager for custom antibodies at Bio-Rad Laboratories,…
LC–MS/MS strategies for therapeutic antibodies and investigation into the quantitative impact of antidrug-antibodies
In this original research article, the authors present two novel, high-throughput LC–MS/MS strategies for quantification of monoclonal antibodies in human serum and examine the potential impact of antidrug antibodies.
View webinar on demand Do you spend time generating, selecting and qualifying antibodies for development…
Best practice recommendations for the transfer of cell-based assays for the measurement of neutralizing anti-drug antibodies
The authors present lessons learned from two cell-based assay transfers that met relevant challenges while implementing alternative permutations of the recommended method transfer process.
View webinar The performance of an antibody in an assay often correlates with its…
Sensitive assays enable detection of serum IgG antibodies against Clostridium difficile toxin A and toxin B in healthy subjects and patients with Clostridium difficile infection
The authors invesitgate titer-based assays as a means of assessment of antitoxin A and antitoxin B IgG antibodies as potential biomarkers to identify patients with CDI at increased risk for CDI recurrence.
Interview with Christian Frisch (Bio-Rad Laboratories) on anti-idiotypic antibodies for PK assays and HuCAL® technology
View our interview with Christian Frisch (Bio-Rad AbD Serotec) at the 8th EBF Open Meeting.
In this chapter biosimilar monoclonal antibodies are introduced and the associated structural and analytical issues are discussed.