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Read time: 3:45 mins
Find out more about the immunogenicity of antibody–drug conjugates (ADCs) in this column from Corinna Fiorotti, Business Development Director at BioAgilytix (NC, USA).
Optimizing NBE PK/PD assays using the Gyrolab Affinity Software; conveniently within the bioanalyst’s existing workflow
Learn about the optimization of NBE PK/PD assays utilizing the Gyrolab Affinity Software and find out more about the author in this journal article from Bioanalysis.
Read time: 3 mins
We talk to Maria Myzithras about Optimizing NBE PK/PD assays using the Gyrolab Affinity Software following her latest publication in Bioanalysis.
Researchers from King Saud University (Riyadh, Saudi Arabia) have developed a new ELISA technique, with increased sensitivity and selectivity, for the simple monitoring of bevacizumab levels in blood plasma.
In this month long feature, we bring you a collection of content focusing on the ‘hot topic’ of immuno-oncology.
Immunoprecipitation middle-up LC–MS for in vivo drug-to-antibody ratio determination for antibody–drug conjugates
In this article from Bioanalysis, the authors present a middle-up LC–MS approach for DAR analysis using prelabeled capture beads and in-house fabricated slit-plates.
Drug-target complex specific antibodies: In this interview we talk to Michael Schwenkert (Bio-Rad Laboratories) about the poster he presented at EBF 2017.
Method establishment for discerned immunogenicity assessment of a recombinant glycoprotein containing nonhuman sialic acid Neu5Gc residues
This research article describes a validated electrochemiluminescent method for the detection of antidrug antibodies against both protein and Neu5Gc-containing glycan epitopes.
MorphoSys (Munich, Germany) has announced that its licensee Janssen (Beerse, Belgium) has gained approval for Tremfya® in Europe. The monoclonal antibody is used for the treatment of plaque psoriasis.