Brendan Griffin (University College Cork, Ireland) discusses his work in early drug development in this interview with Bioanalysis Zone. Brendan talks about the most common challenges faced as well as key trends in the field of developability.
After an uncertain start to 2020, the organizing committee of the Workshop in Recent Issues in Bioanalysis (WRIB; 15–29 June 2020) converted the meeting that was due to take place in Phoenix (AZ, USA) to a virtual platform. In this round-up, we summarize some of our highlights from attending the virtual conference.
A simple sweat collection and analysis device from Penn State University (PA, USA) and Xiangtan University (Xiangtan, China) could assist healthcare professionals with diagnosising and monitoring disease progression by measuring biomarkers, such as pH and glucose.
White Paper – EBF recommendation on practical management of critical reagents for antidrug antibody ligand-binding assays
In this White Paper from Bioanalysis, the authors discuss the European Bioanalysis Forum’s recommendations for critical reagents (CR) for immunogenicity assays. They present the requirements for CR and describe the consequences of introducing new lots of CR to immunogenicity assays.
In this interview, Timothy Garrett (University of Florida, FL, USA) discusses the use of MS in his research, some of the key differences between imaging MS and LC–MS and gives some top tips for method development.
With a wealth of on demand presentations, live recordings, short courses and poster sessions made accessible in offices and homes across the world, ASMS 2020 Reboot was a pleasure to attend. We summarize some of our highlights from the virtual conference.
Critical reagent screening and characterization: benefits and approaches for protein biomarker assays by hybrid LC–MS
In this perspective article from Bioanalysis, the authors discuss the similarities and differences of critical reagents in LBAs and hybrid LC–MS assays. The authors propose that the benefits of well-characterized hybrid LC–MS assay reagents are frequently underestimated.
We carried out a survey to gain an insight into the trends, challenges and future outlook for biomarker discovery. We would like to thank everyone who took part in the survey – make sure you check out the results in our infographic.
Since 2013 the short course teaching best practice for maintaining and troubleshooting LC–MS systems has been delivered at the ASMS conference. Ahead of the virtual ASMS 2020 Reboot, we caught up with the course instructors to see what’s new.
Validation of methods for determining pediatric midazolam using wet whole blood and volumetric absorptive microsampling
In this methodology article from Bioanalysis, authors outline the validation of methods for determining pediatric midazolam using wet whole blood and volumetric absorptive microsampling.