Can bioanalysis be aimed without convergence of specificity and selectivity? Is it possible to converge both the strategies? Find out more in this article from Bioanalysis, where the authors discuss the merits and challenges of bioanalysis in terms of specificity versus selectivity in order to find the solutions.
Best practices in performing flow cytometry in a regulated environment: feedback from experience within the European Bioanalysis Forum
In this manuscript, the European Bioanalysis Forum presents additional practice guidance on the use of flow cytometry in the support of drug development programs and addresses areas that are not covered in the previous publications.
We have developed a simple, cost-effective, and labor-efficient two-step protocol for preparing adherent cells for…
Flow cytometry is increasingly recognized as an invaluable technology in biomarker research. Owing to its multiparametric nature it can provide highly detailed information on any single cell in a heterogeneous population. Find out more in this review from Bioanalysis.
Synthetic cannabinoids in biological specimens: a review of current analytical methods and sample preparation techniques
Read more of this critical review regarding the human biological samples that can be used for the determination of synthetic cannabinoids, from Bioanalysis.
Quantitative biodistribution of biotherapeutics at whole body, organ and cellular levels by autoradiography
Tools for mapping and quantifying monoclonal antibody (mAb) and peptide biotherapeutics distribumtion were evaluated by comparing data from three independent methods conducted at the whole body, organ or tissue, and cellular levels.
In this Editorial from Bioanalysis, the authors consider the future for hybrid assays following the US FDA recently issued guidance for hybrid assays. Find out more and access the full article, exclusively for Bioanalysis Zone members.
Find out more about the current situation for biomarker research in Japan in this Editorial from Bioanalysis.
Definitive profiling of plasma bile acids as potential biomarkers for human liver diseases using UPLC–HRMS
Find out more about this investigation into a thorough and rapid profiling of bile acids in human plasma in this article from Bioanalysis.
Find out more about the consequences of utilizing biomarker assays in drug development without being validated correctly, in this Perspective from Bioanalysis.