Browsing: Diagnostics

Diagnostics involves the process of determining the nature and circumstances of a diseased condition. A diagnostic assay is often used in clinical decision-making for an individual patient. Diagnostic assays generally fall into one of six categories:

  • Assays that screen for disease in an apparently health population;
  • Assays used to aid in the diagnosis of a particular disease;
  • Assays that monitor a disease or the efficacy of its treatment;
  • Assays that stratify risk for a particular disease;
  • Assays that prognose the natural course of a disease or condition;
  • Assays that predict response to a therapeutic intervention often called a ‘companion diagnostic’ [1].
  1. Bioanalysis Zone Glossary
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Scientists from Massachusetts Institute of Technology (MA, USA) have developed a urine test that can identify proteins associated with lung cancer. It is hoped the nanoparticle-based test could reduce the quantity of false positives and improve early detection.

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Researchers from Mologic Ltd (Bedford, UK) have announced that they are currently validating a COVID-19 diagnostic test with the Liverpool School of Tropical Medicine (UK), St Georges’ University (London, UK).

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Scientists at the Johns Hopkins Kimmel Cancer Center (MD, USA) have completed a proof-of-principle study with results indicating the potential for a urine test for prostate cancer. The study identified cancer-specific changes in urinary RNAs and metabolites.

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