In this editorial, Robert MacNeill (Envigo) dicusses the case for the surrogate analyte approach for biomarker validation.
Find out more about ensuring the validity of biomarker measurements in this Editorial from Liam Heaney (University of Loughborough, UK).
Read time: 3:45 mins
Find out more about the immunogenicity of antibody–drug conjugates (ADCs) in this column from Corinna Fiorotti, Business Development Director at BioAgilytix (NC, USA).
Read time: 4:30 mins
In this column, Afshin Safavi differentiates between ‘assay qualification’ and ‘assay validation’ explaining current industry guidance, the translation of this guidance into the exploratory biomarker world, and how BioAgilytix (NC, USA) approaches these challenges.
Read time: 4:30 mins
In this editorial, Albert Koulman discusses whether a routine approach to lipidomic analysis may be possible, and what challenges may need to be considered for this to be the case.
Read/watch time: 3 mins
Learn more about the field of lipidomics in this FAQ style ‘Ask the Editor’ article about the fundamentals of lipidomic analysis.
In this installment of Robert MacNeill’s (Envigo) column, Robert discusses how to increase column plate count – the most obvious way!
The fourth in our monthly column series highlighting the ‘hot topics’ throughout November.
Mass spectrometry based metabolomics: a novel analytical technique for detecting metabolic syndrome?
This editorial discusses the use of mass spectrometry metabolomics as a diagnositic tool for detecting metabolic syndrome. Learn more in this article from Bioanalysis.
Ion mobility spectrometry combined with high-resolution mass spectrometry: acquisition, analysis and application to drug metabolism studies
In discovery, the identification of the major routes of biotransformation allows medicinal chemists to design compounds with more desirable ADME properties. Dan and Jan discuss the use of ion mobility spectrometry combined with high-resolution mass spectrometry for these drug metabolism studies.