In this conference report we discuss our highlights from the 11th Open Meeting of the European Bioanalytical Forum – Raise the Anchor, Set Sail for Science (Barcelona, Spain; 21–23 November).
Find out more an electrochemiluminescent bridging immunogenicity assay used to measure anti-drug antibodies in human serum using an acid dissociation step in this poster from KCAS Bioanalytical & Biomarker Services (KS, USA).
All immunogenicity assessments present specific challenges. As a contract research organization (CRO), a major challenge we face is related to the lack of harmonization and standardization. Find out more in this editorial from a team at LGC (Cambridgeshire, UK).
Application of Mitra® Microsampling for Pharmacokinetic Bioanalysis of Monoclonal Antibodies in Rats
In this methodology article from Bioanalysis, H Li et al. describe the use of the Mitra® microsampler for blood sampling, ELISA quantitation and PK analysis of two marketed therapeutic monoclonal antibodies administered to rats.
As part of our Spotlight on immunogenicity, we carried out a survey to gain an insight into the trends, challenges and developments associated with immunogenicity testing. We would like to thank everyone who was able to share their thoughts by taking part in the survey.
In this feature, we will be investigating different alternative matrices that are available to the bioanalytical scientist and what questions need to be asked when deciding on the appropriate matrix to answer specific bioanalytical questions.
In this interview Alex Hawes (LGC; Cambridge, UK) discusses the topic of immunogenicity. She explains how she developed her first anti-drug antibody analytical method and the platforms LGC use in their immunogenicity sector.
Find out more about working with immunogenicity as well as what the future may hold for the field in this interview with Joyce Slusser (KCAS).
Dr Bonner serves as a scientific resource and technical advisor for both clients and internal…
In this feature, we follow up with our previous winners to get their tips and advice for those starting out in bioanalysis.