In this review from Bioanalysis, the authors concisely introduce coated blade spray’s operational fundamentals and to consider how it correlates/contrasts with existing direct-to-MS technologies suitable for bioanalytical applications.
Browsing: Journal Articles
In this perspective piece, a general discussion on the importance of these matrix effects is provided as well as how to properly address them in the method-development and validation stages of regulated bioanalysis.
Expanding lipidome coverage using MS/MS-aided untargeted data-independent RP–UPLC–TOF–MSE acquisition
Learn more about lipidome coverage using MS/MS-aided untargeted data-independent RP–UPLC–TOF–MSE acquisitionin this journal article from Bioanalysis.
Evaluating lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometry
Learn more about the evaulation of lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometyry in this article from Bioanalysis.
Pharmacokinetic determination and analysis of nortriptyline based on GC–MS coupled with hollow-fiber drop-to-drop solvent microextraction technique
Find out more about how simple, sensitive and robust technique of hollow-fiber drop-to-drop solvent microextraction coupled with GC–MS has been successfully developed for the detection of antidepressant drug nortriptyline in human blood and urine samples in this article from Bioanalysis.
Find out more about graphical evaluation of unmatched incurred sample reanalysis in this article published in Bioanalysis.
In this review, the authors discuss supercritical fluid chromatography and review the advantages and disadvantages of the method.
Immunogenicity of therapeutic protein products: current considerations for anti-drug antibody assay in Japan
In this review, the authors introduce the current situation regarding the development and immunogenicity assessment of therapeutic protein products in Japan. Then they present their view and recommendations on the ADA assay by considering its unique features.
Coinciding with the Chinese New Year, on Bioanalysis Zone we have a focus on the bioanalytical work carried out in China.
Assessing a multiplex targeted proteomics approach for the clinical diagnosis of periodontitis using saliva samples
This study from Bioanalysis focused on the research of new biomarkers based on the liquid chromatography-multiple-reaction monitoring (MRM) proteomic profile in whole saliva.