Discover more about new μFLC technologies that are providing discovery bioanalytical scientists with an effective strategy for method development and optimization in this article from Bioanalysis.
Browsing: Journal Articles
In this article from Bioanalysis, the authors give their perspectives and findings in exploring a hybrid LBA/LC–MS as an orthogonal bioanalytical tool for clinical immunogenicity assessments.
Microflow UPLC and high-resolution MS as a sensitive and robust platform for quantitation of intact peptide hormones
In this research article the authors discuss the use of high-resolution mass spectrometry for basic characterization and reliable quantitation in complex matrices.
Discover more about a possible new avenue, free of ion-pairing, for general application in oligonucleotide quantitative LC–MS discovered by researchers in this methodology from Bioanalysis.
In this research article from Bioanalysis the authors discuss the quantitation of larger biotherapeutic proteins such as antibodies and antibody–drug conjugates compared with small molecules by LC–HRMS.
A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers
This preliminary communication from Bioanalysis discusses the application of selected bile acids in plasma as endogenous probes for assessing drug–drug interactions involving hepatic drug transporters such as the organic anion-transporting polypeptides.
Development of two complementary LC–HRMS methods for analyzing sotatercept in dried blood spots for doping controls
In this research article from Bioanalysis the authors discuss the role of alternative matrices such as dried blood spots in sports drug testing, and the advantages these methods have over conventional matrices.
Recommendations for classification of commercial LBA kits for biomarkers in drug development from the GCC for bioanalysis
In this White Paper from Bioanalysis the authors highlight the need the bioanalytical community has for commercial kits able to be used for regulated drug development.
In this report from Bioanalysis, the authors summaries key points discussed the Bioanalysis Zone panel discussion filmed during the 12th Workshop on Recent Issues in Bioanalysis which focused on the topic of new technology integration into bioanalytical workflows.
This commentary from Bioanalysis focuses on the status of drug detection with metal nanoparticles as ultrasmall labels in colorimetric-based methods.