Researchers have developed a new microfluidic device that enables simultaneous double sorting and purification of target cells.
In this opinion piece, Ming Li proposes adopting automation to address current turnover and data quality challenges faced by Chinese bioanalytical CROs.
Validation of an integrated series of ligand-binding assays for the quantitative determination of antibody–drug conjugates in biological matrices
In this manuscript the authors describe the validation of the three ligand binding bioanalytical assays utilizing highly specific reagents pivotal to current bioanalytical strategy to measure total antibody, active ADC and total ADC.
In this commentary the author suggests automation of workflows can help ensure high quality data at Chinese CRO’s, where the turnover of staff is high, and many inexperienced staff carry out bench work.
This research article details the development of a robust small-molecule bioanalytical sample preparation method.
In this special report the authors review the most commonly used online sample extraction methodologies including online SPE, turbulent flow chromatography, online DBS extraction and online immunoaffinity extraction.
In this article an investigation into elucidating parameters for optimized generic DBS direct elution for high sample throughput quantitative bioanalytical applications is presented.
Cameron Low interviews Rob Durham, Director of Field Applications Scientists, North America, Gyros on automation of assays and the Gyros Immunoassay.
In this commentary Joe Tweed (Pfizer) discusses how fully leveraging automation in the bioanalytical laboratory requires considerations that should include the supporting logistics and biospecimen management practices routinely used in the laboratory.
Webinar Q&A follow up: ‘High-throughput mass spectrometric analysis of covalent protein-inhibitor adducts for the discovery of irreversible inhibitors: a complete workflow’
This article features the presenters’ responses to unanswered audience questions posed during the live webinar ‘High-throughput mass spectrometric analysis of covalent protein-inhibitor adducts for the discovery of irreversible inhibitors: a complete workflow’.