Find out more about a novel biosensor for the real time oxygen monitoring for organ-on-a-chip systems, and a liquid biopsy for predicting lymphoma therapy success.
Browsing: Drug Discovery and Development
Find out more about the technologies involved in drug metabolism and what the future may hold for drug metabolism studies in drug discovery research in this ‘In the Zone’ feature.
As part of our ‘In the Zone’ feature on drug metabolism, we present the top 6 tips for LC–MS for drug metabolism studies. Find out more about best practice tip and tricks for LC–MS in this helpful infographic from MilliporeSigma (MO, USA).
In this podcast, Kevin Ray (MilliporeSigma) discusses the techniques and technologies utilized in drug metabolism studies for biotherapeutics, and what he believes the future holds for the field.
Validated UHPLC–MS/MS method for quantification of doxycycline in abdominal aortic aneurysm patients
Read more about this development and validation of a selective, specific, simple and rapid UHPLC–MS/MS method for doxycycline, in our featured article from Bioanalysis.
Read more about the valdiation of an ELISA to investigate the pharmacokinetics and concentration–response relationship of panitumumab, in this article from Bioanalysis.
Find out more about graphical evaluation of unmatched incurred sample reanalysis in this article published in Bioanalysis.
Combined mass spectrometry with robotic technologies technique could rapidly speed up drug discovery
Researchers at Purdue University (IN, USA) have developed a technique to speed up high-throughput screening by up to ten times.
Researchers have demonstrated that small molecules mimicking activated protein C could provide anti-inflammatory and anti-thrombotic protection without interfering with blood clotting, becoming attractive drug candidates.
The first biosimilar for the treatment of breast and stomach cancers has been approved by the FDA, termed Ogivri.