Find out more about graphical evaluation of unmatched incurred sample reanalysis in this article published in Bioanalysis.
Browsing: Drug Discovery and Development
Combined mass spectrometry with robotic technologies technique could rapidly speed up drug discovery
Researchers at Purdue University (IN, USA) have developed a technique to speed up high-throughput screening by up to ten times.
Researchers have demonstrated that small molecules mimicking activated protein C could provide anti-inflammatory and anti-thrombotic protection without interfering with blood clotting, becoming attractive drug candidates.
The first biosimilar for the treatment of breast and stomach cancers has been approved by the FDA, termed Ogivri.
MorphoSys (Munich, Germany) has announced that its licensee Janssen (Beerse, Belgium) has gained approval for Tremfya® in Europe. The monoclonal antibody is used for the treatment of plaque psoriasis.
For therapeutic drug development and monitoring, microsampling technology provides a breakthrough alternative
One useful way to think about volumetric absorptive microsampling (VAMS) technology is as the next generation of traditional dried blood spot (DBS) cards. It’s a simpler method that makes it easier to collect blood and prepare it for analysis. With minimal training, the microsampling process can be self-administered anywhere, through a procedure that is less difficult and generally less expensive than working with conventional venous blood. Other benefits include a more pleasant patient experience, which leads to greater adherence and compliance, and freer access to remote areas of the world.
All biological protein drugs are immunogenic, which may lead to severe clinical consequences. This makes knowledge of the scientific and regulatory aspects of immunogenicity a must for every drug manufacturer.
Biotechnology company, BIOCAD (St. Petersburg, Russia), announced that its rituximab biosimilar has received recommendation for approval in India.
Novel ‘heart-on-a-chip’ technology could measure compound effects on heart tissue function in the hope of ensuring safety and efficiently of new drugs.
A blood test could predict how men diagnosed with advanced prostate cancer respond to targeted disease treatments.