In this interview, Robert Durham gives an overview of the new Gyrolab® xPand from Gyros Protein Technologies, presented at WRIB this year.
Browsing: Drug Discovery and Development
In this interview, Song Li from Frontage Laboratories (PA, USA) discusses the key challenges of outsourcing in the bioanalytical field, as well as his thoughts and perspectives on what the future holds for the relationship between CROs and pharma.
Validated UHPLC–MS/MS method for quantification of doxycycline in abdominal aortic aneurysm patients
Read more about this development and validation of a selective, specific, simple and rapid UHPLC–MS/MS method for doxycycline, in our featured article from Bioanalysis.
Read more about the valdiation of an ELISA to investigate the pharmacokinetics and concentration–response relationship of panitumumab, in this article from Bioanalysis.
Find out more about graphical evaluation of unmatched incurred sample reanalysis in this article published in Bioanalysis.
Combined mass spectrometry with robotic technologies technique could rapidly speed up drug discovery
Researchers at Purdue University (IN, USA) have developed a technique to speed up high-throughput screening by up to ten times.
Researchers have demonstrated that small molecules mimicking activated protein C could provide anti-inflammatory and anti-thrombotic protection without interfering with blood clotting, becoming attractive drug candidates.
The first biosimilar for the treatment of breast and stomach cancers has been approved by the FDA, termed Ogivri.
MorphoSys (Munich, Germany) has announced that its licensee Janssen (Beerse, Belgium) has gained approval for Tremfya® in Europe. The monoclonal antibody is used for the treatment of plaque psoriasis.
For therapeutic drug development and monitoring, microsampling technology provides a breakthrough alternative
One useful way to think about volumetric absorptive microsampling (VAMS) technology is as the next generation of traditional dried blood spot (DBS) cards. It’s a simpler method that makes it easier to collect blood and prepare it for analysis. With minimal training, the microsampling process can be self-administered anywhere, through a procedure that is less difficult and generally less expensive than working with conventional venous blood. Other benefits include a more pleasant patient experience, which leads to greater adherence and compliance, and freer access to remote areas of the world.