Winner of the 2019 BOSCA announced!
Bioanalysis Zone is proud to announce the 2019 Bioanalysis Outstanding Contribution Award winner – find out who has won this year’s award here!
Browsing: Mass Spectrometry
Optimization of microflow LC–MS/MS and its utility in quantitative discovery bioanalysis
Discover more about new μFLC technologies that are providing discovery bioanalytical scientists with an effective strategy for method development and optimization in this article from Bioanalysis.
Perspectives on exploring hybrid LBA/LC–MS approach for clinical immunogenicity testing
In this article from Bioanalysis, the authors give their perspectives and findings in exploring a hybrid LBA/LC–MS as an orthogonal bioanalytical tool for clinical immunogenicity assessments.
LC–HRMS quantitation of intact antibody drug conjugate trastuzumab emtansine from rat plasma
In this research article from Bioanalysis the authors discuss the quantitation of larger biotherapeutic proteins such as antibodies and antibody–drug conjugates compared with small molecules by LC–HRMS.
A multiplex HRMS assay for quantifying selected human plasma bile acids as candidate OATP biomarkers
This preliminary communication from Bioanalysis discusses the application of selected bile acids in plasma as endogenous probes for assessing drug–drug interactions involving hepatic drug transporters such as the organic anion-transporting polypeptides.
Advancing mass spectrometry technologies: an interview with Neil Walsh
Hear more about the recent mass spectrometry product launches from SCIEX announced at ASMS 2019, including the new Acoustic Ejection Mass Spectrometry technology, in this interview with Neil Walsh (SCIEX; MA, USA).
ASMS 2019 conference report
In this conference report we discuss our highlights from the 67th American Society for Mass Spectrometry (ASMS; GA, USA; 2–6 June).
Signal amplification technology reveals previously undetectable proteins of disease
An isobaric labeling technique has been developed to amplify signals for comprehensive quantitative phosphoproteomic characterization of small cells populations.
An author’s perspective: Zhengqi Ye on approaches to measure protein binding of enzymatically unstable compounds
We talk to Zhengqi Ye about the approaches she uses to measure protein binding of enzymatically unstable compounds in plasma in this interview as part of our author’s perspective series.
An author’s perspective: Laura Rowe on analyzing protein glycosylation using UHPLC
We talk to Laura Rowe about her work using UHPLC to analyse protein glycosylation in this interview as part of our author’s perspective series.