Find out more about some of the top stories this week in methodological improvements for the quantitative analysis of proteomes, and for the production of chiral molecules.
Opportunities and challenges for hybrid immunoaffinity LC–MS approach for quantitative analysis of protein biomarkers
Learn more about opportunities and challenges for hybrid immunoaffinity LC–MS approach for quantitative analysis of protein biomarkers in this article from Future Science OA.
This infographic presents key results from the large molecule quantification by LC–MS survey.
Read time: 2 mins
Read more about the latest advances in proteomics this week in our themed weekly news round-up, including news regarding a new clinical market license for a predictive diagnostic test for diabetic kidney disease, and a new device for in vivo real-time proteomics in surgical oncology.
In this interview, Nico and Chad (PRA Health Sciences; NC, USA) discuss the advantages, disadvantages and challenges they face with the technologies they utilize, before predicting what the future holds for the field.
In this interview, Jun Qu (University at Buffalo; NY, USA) describes his current research focuses, including the technologies he is currently developing. Jun goes on to discuss the challenges involved in implementing sensitive quantifications of biotherapeutics using LC–MS and speculates on the future of the technology.
Proposal for risk-based scientific approach on full and partial validation for general changes in bioanalytical method
This manuscript, from Bioanalysis, presents perspectives and recommendations for most conceivable changes that can be made to full and partial validations by members of the discussion groups based on their experiences and discussions at the Japan Bioanalysis Forum Symposium.
Rob Wheller, Principal Scientist from LGC (Fordham, UK), discusses his current research focuses; the advantages, disadvantages and challenges of the technologies he utilizes; and advice he would give to young, early-career scientists.
Read time: 1:30 mins
Read more about the top advances in bioanalysis for neurological sciences, including a biomarker for autism and a novel method utilizing a combination of probe electrospray ionization (PESI) and tandem mass spectrometry (MS/MS) for imaging metabolites in a live mouse brain.
Validated UHPLC–MS/MS method for quantification of doxycycline in abdominal aortic aneurysm patients
Read more about this development and validation of a selective, specific, simple and rapid UHPLC–MS/MS method for doxycycline, in our featured article from Bioanalysis.