Avoid preclinical testing failure by understanding the complex bioanalytical and toxicology challenges associated with ADC drug development and unique ways to overcome them.
Determination of propranolol and carvedilol in urine samples using a magnetic polyamide composite and LC–MS/MS
In this work, the authors have synthesized a new composite based on the combination of MNPs and polyamide polymers that has been evaluated in the bioanalytical context for the first time.
Researchers have developed a microneedle drug monitoring system that could provide an alternative to invasive blood tests and improve patient comfort.
Using a novel nanoflower concept, researchers have developed a quick and accurate sensor for E. coli detection.
Determination of free and conjugated forms of endocrine-disrupting chemicals in human biological fluids by GC−MS
The primary purpose of this study was the optimization and validation of a sensitive method for the simultaneous determination of the total content of EDCs using a continuous SPE system combined with GC–MS.
Multiple stage MS in analysis of plasma, serum, urine and in vitro samples relevant to clinical and forensic toxicology
In this article the authors review the application of MS approaches to metabolism studies, structure elucidation and qualitative or quantitative screening of drugs (of abuse) and/or their metabolites.
Study calls for further investigation of synthetic cathinones to aid detection of illegal substances
A new report calls for analytical methods to keep pace with the development of synthetic cathinones, or bath salts, an ever evolving class of designer drug that are difficult to detect in biological samples.
Bioanalytical procedures and developments in the determination of alcohol biomarkers in biological specimens
This review covers topics for an analyst to consider when evaluating alcohol consumption through the analysis of alcohol biomarkers.
Interview with Tim Sangster and Kurt Sales (Charles River Laboratories) on the developing CRO industry and the challenges faced by sponsors
View our interview with Tim Sangster and Kurt Sales (Charles River Laboratories) at the 8th EBF Open Meeting.
Galderma, a leading pharmaceutical company in Dermatology, has chosen ImaBiotech to support their drug development with innovative Multimaging™ services.