Commentaries

In the Zone
0 In the Zone: biotransformation

In this feature, we present a collection of resources focusing on the ‘hot topic’ of biotransformation, including: an introduction to what it is, a podcast discussing the technologies used to characterize biotransformation and an infographic with our top 5 challenges for the biotransformation scientist and software solutions.

Biomarkers
0 Novel ADME biomarkers and HRMS move new medicines to patients faster

In this interview with Ragu Ramanathan (Pfizer; NY, USA), Ragu describes his current research focuses in measuring and quantitating drugs and metabolites in animal and human samples. Ragu discusses the key challenges associated with studying drug/drug interactions (DDI), the benefits of current technologies available for studying DDI and what to expect from the upcoming Special Focus Issue from Bioanalysis on ‘Novel LC–MS assays impacting CYP and transporter DDI evaluation’.

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