Mission multiplex: mastering your biomarker journey with the MILLIPLEX® PLEXpedition Screening Panel

Immunoassays are a cornerstone of life science research, offering scientists a powerful method to detect and quantify specific proteins, hormones and other analytes with remarkable sensitivity and specificity. These assays play a critical role in advancing our understanding of biological systems, disease mechanisms and therapeutic responses. Traditionally, most immunoassays have been singleplex, which probe a single analyte per experimental run, but while valued, this approach is time-intensive and consumes valuable sample volumes.

Multiplex assays overcome these limitations by enabling simultaneous probing of dozens to hundreds of analytes per run, conserving valuable samples and time, and technological advancements like the MILLIPLEX^® PLEXpedition Screening Panel take this innovation to the next level. The panel offers numerous advantages that address critical challenges in biomarker research, including a matrix-free format for enhancing detection across diverse sample types, seamless transition to qualified panels with reproducible quantification, and improved research efficiency through sample conservation.

This In the Zone feature will explore key aspects of MILLIPLEX^® Screening and Qualified Assays, the advantages of using the MILLIPLEX^® PLEXpedition Screening Panel and expert top tips and tricks, including troubleshooting advice, when using MILLIPLEX^® platforms and instruments.

[Video by James Harvie]

INFOGRAPHIC

The PLEXpedition Path: your guide to biomarker discovery and verification with MILLIPLEX^® assays

This infographic explores the complete biomarker journey using MILLIPLEX^® multiplex assays and Luminex^® instruments, showcasing technology benefits, seamless transitions from discovery to verification, and expert troubleshooting advice to help researchers navigate common challenges and optimize their multiplex protein detection workflows.

INTERVIEW

115 analytes, one panel: a conversation on innovation in biomarker discovery

This podcast episode features Dr Sean Kimbro and Kenisha Webb from the Morehouse School of Medicine (GA, USA) discussing how the MILLIPLEX^® PLEXpedition Screening Panel and Luminex^® xMAP^® INTELLIFLEX^® system are advancing their biomarker research by enabling comprehensive multi-analyte studies, addressing common screening challenges and providing practical advantages through efficient measurement of multiple biomarkers in one test rather than separate individual assays.

RESOURCES

Ranked abundance of 115 proteins following simultaneous measurement by multiplex immunoassay in serum, plasma, and cell culture supernatant samples

Profiling 115 proteins in colon and duodenal organoid supernatants by multiplex immunoassay

For Research Use Only. Not For Use In Diagnostic Procedures.

In association with:

The Life Science business of Merck operates as MilliporeSigma in the US and Canada.