Phospholipids can impart detrimental effects on LC/MS/MS analysis including ion suppression, build up on the MS source and decreased column lifetime due to build up on the HPLC column. Phree removes >99% of phospholipids from bioanalytical samples which eliminates the aforementioned negative effects.
Other products in Chromatography
Phree Phospholipid Removal Solutions offer a fast effective way to remove proteins and phospholipids from plasma samples without negatively affecting the recovery of your target analytes. The Solvent Shielding Technology™ design of the Phree Phospholipid Removal products will withhold organic solvents above the filter membranes for up to 25 minutes, allowing for direct in-well or in-tube precipitation upon the addition of plasma. Once precipitation is complete, the sample is filtered through the Phree sorbent which selectively removes phospholipids, resulting in a protein and phospholipid free sample.
One Quick Method, Four Big Advantages
- Avoid high back pressures by removing proteins that can clog HPLC/UHPLC columns
- Extend HPLC/UHPLC column lifetime by removing phospholipids that can build up on your column
- Eliminate ion-suppression by removing phospholipids
- Skip the method development; one method for acids, bases, and neutrals