Waters launches the Xevo TQ Absolute XR at ASMS 2025
Waters Corporation (MA, USA) launches the Xevo™ TQ Absolute XR Mass Spectrometer at the American Society for Mass Spectrometry (ASMS; 1–5 June, MD, USA) 2025.
ASMS 2025 saw the announcement of Waters’ latest mass spectrometry platform, the Xevo TQ Absolute XR Mass Spectrometer. Tailored for high-throughput applications, the Xevo™ TQ Absolute XR system is Waters’ most sensitive, robust and reliable benchtop tandem quadrupole platform yet. Notably, the product exceeds the performance capabilities of the Xevo TQ Absolute, which set the benchmark in the industry for tandem quadrupole sensitivity, particularly for pharmaceutical quantitation and PFAS detection. The new system is designed to deliver exceptional performance for the most sensitive, trace-level analyses in complex matrices.
“Analytical laboratories are under pressure to adapt to the complex needs of pharmaceutical organizations, and meet the increasing demand for PFAS testing driven by a rapidly evolving regulatory landscape,” explained James Hallam, Vice President, LC–MS, Waters Corporation. “The Xevo TQ Absolute XR design delivers up to a six-fold increase in performance robustness with unmatched sensitivity and resilience to contamination, significantly reducing downtime and enhancing operational efficiency for our customers.”
Built on the intuitive design of the Xevo TQ Absolute, the Xevo TQ Absolute XR system offers significant operational efficiencies. It uses up to 50% less power and nitrogen gas, produces 50% less heat than any other high-performing tandem or triple quadrupole on the market, and takes up to 50% less bench space, making it the ideal system for laboratories striving to reduce their environmental footprint without compromising throughput or performance.
Within the Xevo TQ Absolute XR, Waters introduces the StepWave XR Ion Guide, which incorporates sophisticated technology designed to minimize the risk of unplanned downtime while preserving high sensitivity and precision for even the most complex sample types and fragile compounds.
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“Our laboratory requires instrumentation that delivers high-quality, interruption-free results to our customers, helping them to bring safe and effective new drugs to market with confidence and speed,” said Sally Hannam, Scientific Director, Synexa Life Sciences, a leading biomarker and bioanalytical services provider. “We are well in excess of 20,000 injections of crashed human plasma continuously analyzed on the Xevo TQ Absolute XR Mass Spectrometer combined with the ACQUITY™ Premier UPLC™ System and waters_connect™ Software, and our early experience is that it demonstrates new levels of reproducibility and accuracy, giving us ever more confidence as we are presented with increasingly challenging bioanalysis applications and new modalities.”
