The ABCs of ADCs: From PK to PD

The ABC's of ADCs

Thursday 4 December 2025
07:00 [PST]  10:00 [EST] 15:00 [GMT]

Predictive bioanalytical strategies for the development of Antibody-Drug Conjugates (ADCs)

ADCs often fail because the drug gets to the right tissue, but misses its target. It’s not enough to just seek the concentration of your ADC in the tissue, you need to know its exact location to predict efficacy and move your development program forward with confidence. In this webinar, renowned scientists and industry thought leaders, Troy Voelker, and Corinne Ramos, outline a holistic bioanalytical strategy for your ADC, incorporating traditional bioanalysis with spatial bioanalysis to reveal decision-making data about how your ADC engages with the complex microenvironment.

Join us to learn step by step how to de-risk your ADC program with guidance on assessing:
    • Antibody payload concentration
    • Conjugated antibody concentration
    • Free payload concentration
    • Spatial distribution
    • Target engagement
    • Toxicity

 

REGISTER NOWWhat will you learn?Who may this interest?Speakers


What will you learn?

  • Strategies for the bioanalysis of ADCs
  • The benefits of incorporating spatial bioanalysis into your development strategy
  • How to combine these strategies to predict efficacy

Who may this interest?

  • ADC Drug Developers
  • Individuals interested in large molecule development
  • Antibody development and method development bioanalysis
Troy Voelker

Troy Voelker
Senior Laboratory Director
Aliri Bioanalysis (CO, USA)

Troy is a bioanalytical scientist with a specialization in oligonucleotides and has 20+ years of experience supporting the drug developers with regulatory-ready data. He received a PhD in XX from the Human BioMolecular Research Institute (CA, USA). He is also a member of the AAPS Oligonucleotide Discussion Group and regularly contributes to the advancement of the industry through featured presentations and scientific posters at top bioanalytical conferences like the American Association of Pharmaceutical Scientists (AAPS) PharmSci 360.

 

Corinne Ramos

Corinne Ramos
R&D Director
Aliri Bioanalysis (CO, USA)

Corinne is a biomarker expert with 25+ years of experience in clinical assay/biomarker development validation and molecular oncology and imaging in oncology/diagnostics. She received a PhD in Molecular Biology from the University Paul Sabatier (Toulouse, France) and an MBA from the Johns Hopkins University-Carey Business School (Washington DC, USA). Corinne has published numerous scientific papers, given presentations at industry-leading conferences like European Bioanalysis Forum (EBF) and is well-known for her work integrating AI with spatial-omics to predict patient outcomes.

 

In association with:

Aliri Bioanalysis