Publication / Source: Bioanalysis 3(11)
Authors: Resau J
“Whereas most research specimens are examined retrospectively for determinants of disease, we believe we will soon be able to prospectively diagnose genetics-based conditions using biospecimens collected before presentation of disease conditions…”
There is an economic maxim that one is more likely to efficiently obtain results from modification or improvement of an existing successful system than by building a brand new system from scratch. Consider, for example, if one wanted to ethically obtain biologic samples from every person born in the USA in order to create a biospecimen resource that could realize the promises of evidence-based medicine, the issues of cost, ethics, complexity and selection would render the project stillborn – as well as incompatible with the NIH mantra of funding only hypothesis-based research and not ‘fishing expeditions’.